EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROUSSOFLAVONOL B IN A MODEL OF INDUCED PLANTAR EDEMA IN LABORATORY MICE

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F25%3A00144404" target="_blank" >RIV/00216224:14160/25:00144404 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROUSSOFLAVONOL B IN A MODEL OF INDUCED PLANTAR EDEMA IN LABORATORY MICE

Popis výsledku v původním jazyce

Prenylated phenols are natural substances that are used in traditional medicine for their wide range of biological effects. Broussoflavonol B was isolated from Broussonetia papyrifera with various biological activities, such as antioxidant, and anti-inflammatory activity. The anti-inflammatory activity of broussoflavonol B has been described in vitro, and inhibition of NF-κB and IL-1β activity has been demonstrated. The next step in the investigation of the biological activity of these natural compounds is to verify their anti-inflammatory potential in vivo. The experiment follows the previous in vitro research phases, which confirmed the anti-inflammatory activity of the selected natural substances.

Název v anglickém jazyce

EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROUSSOFLAVONOL B IN A MODEL OF INDUCED PLANTAR EDEMA IN LABORATORY MICE

Popis výsledku anglicky

Prenylated phenols are natural substances that are used in traditional medicine for their wide range of biological effects. Broussoflavonol B was isolated from Broussonetia papyrifera with various biological activities, such as antioxidant, and anti-inflammatory activity. The anti-inflammatory activity of broussoflavonol B has been described in vitro, and inhibition of NF-κB and IL-1β activity has been demonstrated. The next step in the investigation of the biological activity of these natural compounds is to verify their anti-inflammatory potential in vivo. The experiment follows the previous in vitro research phases, which confirmed the anti-inflammatory activity of the selected natural substances.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

30500 - Other medical sciences

Projekt

<a href="/cs/project/GA23-04655S" target="_blank" >GA23-04655S: Role prenylace a glykosylace v protizánětlivé aktivitě a metabolismu přírodních fenolových látek</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů