Tří-bloková Bi-fokální PLS (3BIF-PLS) a její použití v QSAR

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F04%3A00010493" target="_blank" >RIV/00216224:14310/04:00010493 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Three-Block Bi-Focal PLS (3BIF-PLS) and its Application in QSAR.

Popis výsledku v původním jazyce

When X and Y are multivariate the two-block partial least squares (PLS) method is often used. In this paper we outline an extension addressing a special case of the three-block (X/Y/Z) problem, where Z sits "under" Y. We call this approach 3BIF-PLS. It views the X/Y relationship as the dominant problem, and seeks to use the additional information in Z in order to improve the interpretation of the Y-part of the X/Y association. Two data sets are used to illustrate three-block bi-focal PLS (3BIF-PLS). Example I relates to single point mutants of haloalkane dehalogenase from Sphingomonas paucimobilis UT26 and their ability to transform halogenated hydrocarbons, some of which are found as organic pollutants in soil. Example II deals with soil remediation capability of bacteria. Whole bacterial communities are monitored over time using "DNA-fingerprinting" technology to see how pollution affects population composition. Since the data sets are large, hierarchical multivariate modeling is inv

Název v anglickém jazyce

Three-Block Bi-Focal PLS (3BIF-PLS) and its Application in QSAR.

Popis výsledku anglicky

When X and Y are multivariate the two-block partial least squares (PLS) method is often used. In this paper we outline an extension addressing a special case of the three-block (X/Y/Z) problem, where Z sits "under" Y. We call this approach 3BIF-PLS. It views the X/Y relationship as the dominant problem, and seeks to use the additional information in Z in order to improve the interpretation of the Y-part of the X/Y association. Two data sets are used to illustrate three-block bi-focal PLS (3BIF-PLS). Example I relates to single point mutants of haloalkane dehalogenase from Sphingomonas paucimobilis UT26 and their ability to transform halogenated hydrocarbons, some of which are found as organic pollutants in soil. Example II deals with soil remediation capability of bacteria. Whole bacterial communities are monitored over time using "DNA-fingerprinting" technology to see how pollution affects population composition. Since the data sets are large, hierarchical multivariate modeling is inv

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BB - Aplikovaná statistika, operační výzkum

OECD FORD obor

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Projekt

<a href="/cs/project/ME%20551" target="_blank" >ME 551: Konstrukce dehalogenujících enzymů pro biotechnologické aplikace</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

SAR and QSAR in Environmental Research

ISSN

ISBN 1029-046

e-ISSN

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Svazek periodika

5-6

Číslo periodika v rámci svazku

15

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

18

Strana od-do

481-499

Kód UT WoS článku

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EID výsledku v databázi Scopus

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