Oxidative stress in enchytraeidae (E. albidus, E. crypticus) - Establishment and optimalization of methods

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F06%3A00016326" target="_blank" >RIV/00216224:14310/06:00016326 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Oxidative stress in enchytraeidae (E. albidus, E. crypticus) - Establishment and optimalization of methods

Popis výsledku v původním jazyce

Oxidative impact of toxic substances is one of a main toxicity mechanisms. In cells, there occurs redox imbalance due to enhanced production of reactive oxygen species (ROS) and/or antioxidants inhibition. Effects of this so-called oxidative stress are damage of substantial macromolecules (DNA, proteins, lipids) and subsequent disturbance of cells either whole organism fyziology. Some compounds from group of environmental pollutants (quinones generally, polycyclic aromatic hydrocarbons and their derivares, etc.) can induce oxidative stress in cells of various groups of soil organisms. In the present study, methods for determination a set of biomarkers (GST, GR, GSH, lipid peroxidation) used as parametres of oxidative stress and toxicity generally wereestablished. Procedures were optimalized for real samples determination in two species ? E. albidus and E. crypticus.

Název v anglickém jazyce

Oxidative stress in enchytraeidae (E. albidus, E. crypticus) - Establishment and optimalization of methods

Popis výsledku anglicky

Oxidative impact of toxic substances is one of a main toxicity mechanisms. In cells, there occurs redox imbalance due to enhanced production of reactive oxygen species (ROS) and/or antioxidants inhibition. Effects of this so-called oxidative stress are damage of substantial macromolecules (DNA, proteins, lipids) and subsequent disturbance of cells either whole organism fyziology. Some compounds from group of environmental pollutants (quinones generally, polycyclic aromatic hydrocarbons and their derivares, etc.) can induce oxidative stress in cells of various groups of soil organisms. In the present study, methods for determination a set of biomarkers (GST, GR, GSH, lipid peroxidation) used as parametres of oxidative stress and toxicity generally wereestablished. Procedures were optimalized for real samples determination in two species ? E. albidus and E. crypticus.

Druh

O - Ostatní výsledky

CEP obor

DK - Kontaminace a dekontaminace půdy včetně pesticidů

OECD FORD obor

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Projekt

<a href="/cs/project/GP525%2F04%2FP159" target="_blank" >GP525/04/P159: Vliv nově rozpoznávaných prioritních perzistentních organických polutantů (POPs) na organismy v půdním ekosystému</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů