Determination of oxidative potential caused by brake wear debris in non-cellular systems
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27360%2F19%3A10236614" target="_blank" >RIV/61989100:27360/19:10236614 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61989100:27640/19:10236614
Výsledek na webu
<a href="https://www.ingentaconnect.com/content/asp/jnn/2019/00000019/00000005/art00055" target="_blank" >https://www.ingentaconnect.com/content/asp/jnn/2019/00000019/00000005/art00055</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1166/jnn.2019.15866" target="_blank" >10.1166/jnn.2019.15866</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Determination of oxidative potential caused by brake wear debris in non-cellular systems
Popis výsledku v původním jazyce
Wear debris from automotive brake systems represents a major source of non-exhaust emissions from road traffic and its production increases with number of cars worldwide. However, impact of brake wear debris on the environment and organisms is still not clear. One of the most possible ways by which these particles may affect living organisms is oxidative stress. Production of reactive oxidative species may cause damage of basic cell components, lipids, proteins, etc. Aim of this study is to perform characterization of airborne and nonairborne fractions of brake wear debris generated during standard dynamometer tests and evaluation of its potential to induce oxidative stress via lipid peroxidation and carbonylation of proteins in non-cellular system. Elemental and phase composition were determined by scanning electron microscopy, Raman microspectroscopy, and X-ray powder diffraction analysis. Carbon in amorphous form and graphite, copper, and iron in form of oxides were identified as major components in both studied fractions. Characteristic size of studied wear particles was evaluated by dynamic light scattering. Both airborne and nonairborne samples showed ability to induce oxidative stress which results from determination of carbonylated proteins.
Název v anglickém jazyce
Determination of oxidative potential caused by brake wear debris in non-cellular systems
Popis výsledku anglicky
Wear debris from automotive brake systems represents a major source of non-exhaust emissions from road traffic and its production increases with number of cars worldwide. However, impact of brake wear debris on the environment and organisms is still not clear. One of the most possible ways by which these particles may affect living organisms is oxidative stress. Production of reactive oxidative species may cause damage of basic cell components, lipids, proteins, etc. Aim of this study is to perform characterization of airborne and nonairborne fractions of brake wear debris generated during standard dynamometer tests and evaluation of its potential to induce oxidative stress via lipid peroxidation and carbonylation of proteins in non-cellular system. Elemental and phase composition were determined by scanning electron microscopy, Raman microspectroscopy, and X-ray powder diffraction analysis. Carbon in amorphous form and graphite, copper, and iron in form of oxides were identified as major components in both studied fractions. Characteristic size of studied wear particles was evaluated by dynamic light scattering. Both airborne and nonairborne samples showed ability to induce oxidative stress which results from determination of carbonylated proteins.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
21001 - Nano-materials (production and properties)
Návaznosti výsledku
Projekt
<a href="/cs/project/LO1203" target="_blank" >LO1203: Regionální materiálově technologické výzkumné centrum - Program udržitelnosti</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2019
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of nanoscience and nanotechnology
ISSN
1533-4880
e-ISSN
—
Svazek periodika
19
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
7
Strana od-do
2869-2875
Kód UT WoS článku
000458402700055
EID výsledku v databázi Scopus
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