Decrease of humic acids AhR mediated activity after irradiation
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F06%3A00016467" target="_blank" >RIV/00216224:14310/06:00016467 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Decrease of humic acids AhR mediated activity after irradiation
Popis výsledku v původním jazyce
The reporter gene in vitro bioassay with H4IIEluc cells was used for determination of AhR mediated activity of HA. H4IIE-luc are stably transfected hepatoma cells with a luciferase reporter gene that is activated via AhR. Irradiation of five different aqueous HA samples were carried out in pyrex tubes using low pressure mercury lamp. Concentrations of irradiated HA samples were 50 mg/L, and irradiation times were from 0 to 37 hours. In this contribution, we summarize our new findings on alteration of AhR mediated activity of irradiated HS under the lab conditions. Additionally, supposed mechanisms of observed irradiation induced decrease in AhR-mediated activity of dissolved HS is discussed.
Název v anglickém jazyce
Decrease of humic acids AhR mediated activity after irradiation
Popis výsledku anglicky
The reporter gene in vitro bioassay with H4IIEluc cells was used for determination of AhR mediated activity of HA. H4IIE-luc are stably transfected hepatoma cells with a luciferase reporter gene that is activated via AhR. Irradiation of five different aqueous HA samples were carried out in pyrex tubes using low pressure mercury lamp. Concentrations of irradiated HA samples were 50 mg/L, and irradiation times were from 0 to 37 hours. In this contribution, we summarize our new findings on alteration of AhR mediated activity of irradiated HS under the lab conditions. Additionally, supposed mechanisms of observed irradiation induced decrease in AhR-mediated activity of dissolved HS is discussed.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
DN - Vliv životního prostředí na zdraví
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GP525%2F05%2FP160" target="_blank" >GP525/05/P160: In vitro modely pro studium endokrinní disrupce - účinky tradičních a nových typů persistentních organických polutantů</a><br>
Návaznosti
Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2006
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů