Polymorphism of DAB genes and variation in parasite species diversity in European populations of chub (Leuciscus cephalus)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F08%3A00042180" target="_blank" >RIV/00216224:14310/08:00042180 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Polymorphism of DAB genes and variation in parasite species diversity in European populations of chub (Leuciscus cephalus)

Popis výsledku v původním jazyce

The polymorphism of major histocompatibility complex (MHC) genes was investigated in relation to parasitism in several populations of chub (Leuciscus cephalus) from different European rivers. The MHC genes are the most polymorphic loci known for vertebrates, whereas tree possible hypotheses of parasite-mediated selection driving an extensive MHC diversity (i.e. overdominance hypothesis, frequency dependent selection hypothesis and hypothesis of optimal number of MHC alleles) have been proposed. Hence, these genes are convenient model for elucidating the host-parasite relationships. It has been predicted that the populations with more genetic variability of MHC will have more diverse array of parasites. The antigens derived from parasites (possible important selective agents) interact with peptide binding region of MHC II molecules, on that account the present study was focused on genetic variability of the exon 2 (DAB1 and DAB3 genes), which encodes the beta 1 domain of the peptide bin

Název v anglickém jazyce

Polymorphism of DAB genes and variation in parasite species diversity in European populations of chub (Leuciscus cephalus)

Popis výsledku anglicky

The polymorphism of major histocompatibility complex (MHC) genes was investigated in relation to parasitism in several populations of chub (Leuciscus cephalus) from different European rivers. The MHC genes are the most polymorphic loci known for vertebrates, whereas tree possible hypotheses of parasite-mediated selection driving an extensive MHC diversity (i.e. overdominance hypothesis, frequency dependent selection hypothesis and hypothesis of optimal number of MHC alleles) have been proposed. Hence, these genes are convenient model for elucidating the host-parasite relationships. It has been predicted that the populations with more genetic variability of MHC will have more diverse array of parasites. The antigens derived from parasites (possible important selective agents) interact with peptide binding region of MHC II molecules, on that account the present study was focused on genetic variability of the exon 2 (DAB1 and DAB3 genes), which encodes the beta 1 domain of the peptide bin

Druh

O - Ostatní výsledky

CEP obor

EG - Zoologie

OECD FORD obor

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Projekt

<a href="/cs/project/LC522" target="_blank" >LC522: ICHTYOPARAZITOLOGIE - centrum základního výzkumu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů