Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F09%3A00036187" target="_blank" >RIV/00216224:14310/09:00036187 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16270/09:00002241

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)

Popis výsledku v původním jazyce

The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenicstimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.

Název v anglickém jazyce

Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)

Popis výsledku anglicky

The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenicstimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DJ - Znečištění a kontrola vody

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Veterinaria Brno

ISSN

0001-7213

e-ISSN

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Svazek periodika

78

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

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Kód UT WoS článku

000267788000019

EID výsledku v databázi Scopus

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