Analysis of the host-parasite interactions in gastric pathogen Cryptosporidium muris
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00044961" target="_blank" >RIV/00216224:14310/10:00044961 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Analysis of the host-parasite interactions in gastric pathogen Cryptosporidium muris
Popis výsledku v původním jazyce
Cryptosporidium (Apicomplexa) is an epicellular parasite infecting gastrointestinal tract of vertebrates, including humans. Cryptosporidiosis is self-limiting disease in healthy hosts; however, it represents a life-threatening problem in immunocompromised individuals because of lack of an effective treatment. The aim of presented study was to examine and optimise procedures, such as rodent inoculation, faeces examinations, oocysts purification and excystation in vitro, for the planned in vitro and in vivo analyses of host-parasite interactions in Cryptosporidium muris. Additional histological observations have been performed to observe pathological effect of parasite on experimentally infected immunocompromised laboratory mice.
Název v anglickém jazyce
Analysis of the host-parasite interactions in gastric pathogen Cryptosporidium muris
Popis výsledku anglicky
Cryptosporidium (Apicomplexa) is an epicellular parasite infecting gastrointestinal tract of vertebrates, including humans. Cryptosporidiosis is self-limiting disease in healthy hosts; however, it represents a life-threatening problem in immunocompromised individuals because of lack of an effective treatment. The aim of presented study was to examine and optimise procedures, such as rodent inoculation, faeces examinations, oocysts purification and excystation in vitro, for the planned in vitro and in vivo analyses of host-parasite interactions in Cryptosporidium muris. Additional histological observations have been performed to observe pathological effect of parasite on experimentally infected immunocompromised laboratory mice.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
EG - Zoologie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2010
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů