Evidence of synergistic toxicity in birds: experimental co-exposures to cyanobacteria and toxic metal (lead) causes immunosuppressions in Japanese quail

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00047662" target="_blank" >RIV/00216224:14310/10:00047662 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Evidence of synergistic toxicity in birds: experimental co-exposures to cyanobacteria and toxic metal (lead) causes immunosuppressions in Japanese quail

Popis výsledku v původním jazyce

Although the role of cyanobacterial metabolites in mass mortalities of wild birds has been discussed, there are only limited experimental data available on cyanobacterial toxicity in birds. The aim of the present study was to estimate the influence of cyanobacterial biomass, lead and immunological challenge in single and combined exposure scenarios on toxicity and biochemical responses in Japanese quail. The 30-day experiment was performed with 4 months old individuals divided into 8 groups. The presentexperimental study was successful in testing the hypothesis that adverse effects of cyanotoxins, heavy metals, and a non-pathogenic immunological challenge combine to enhance avian mortality. Moreover, single exposure to cyanobacterial biomass resultedin hepatic vacuolar dystrophy, while co-exposure with lead in a more severe granular dystrophy.

Název v anglickém jazyce

Evidence of synergistic toxicity in birds: experimental co-exposures to cyanobacteria and toxic metal (lead) causes immunosuppressions in Japanese quail

Popis výsledku anglicky

Although the role of cyanobacterial metabolites in mass mortalities of wild birds has been discussed, there are only limited experimental data available on cyanobacterial toxicity in birds. The aim of the present study was to estimate the influence of cyanobacterial biomass, lead and immunological challenge in single and combined exposure scenarios on toxicity and biochemical responses in Japanese quail. The 30-day experiment was performed with 4 months old individuals divided into 8 groups. The presentexperimental study was successful in testing the hypothesis that adverse effects of cyanotoxins, heavy metals, and a non-pathogenic immunological challenge combine to enhance avian mortality. Moreover, single exposure to cyanobacterial biomass resultedin hepatic vacuolar dystrophy, while co-exposure with lead in a more severe granular dystrophy.

Druh

O - Ostatní výsledky

CEP obor

DJ - Znečištění a kontrola vody

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>O - Projekt operacniho programu

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů