A Japanese quail model of single and combined exposures to cyanotoxins, lead and Newcastle virus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F09%3A00002245" target="_blank" >RIV/62157124:16270/09:00002245 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

A Japanese quail model of single and combined exposures to cyanotoxins, lead and Newcastle virus

Popis výsledku v původním jazyce

While there are reports on avian wildlife mortalities attributed to cyanotoxins, our recent experimental studies showed no mortality in Japanese quails despite significant biochemical, histopathological and subcellular signs of hepatic damage and induction of oxidative stress along with accumulation of microcystins. The present study, therefore, tested the hypothesis that under natural conditions co-exposure to multiple stressors may enhance avian mortality. Japanese quails were exposed to single and combined action of cyanotoxins, lead and live Newcastle vaccination strain. While no deaths were in groups of single exposures, there was 40% mortality in the group of experimental birds receiving both cyanobacterial biomass and lead. There was considerable accumulation of microcystins in the liver tissue of all cyanobacterial biomass exposed birds. There was a drop in haematocrit and haemoglobin concentrations in all lead exposed groups. Both single and combined exposures to cyanobacteria

Název v anglickém jazyce

A Japanese quail model of single and combined exposures to cyanotoxins, lead and Newcastle virus

Popis výsledku anglicky

While there are reports on avian wildlife mortalities attributed to cyanotoxins, our recent experimental studies showed no mortality in Japanese quails despite significant biochemical, histopathological and subcellular signs of hepatic damage and induction of oxidative stress along with accumulation of microcystins. The present study, therefore, tested the hypothesis that under natural conditions co-exposure to multiple stressors may enhance avian mortality. Japanese quails were exposed to single and combined action of cyanotoxins, lead and live Newcastle vaccination strain. While no deaths were in groups of single exposures, there was 40% mortality in the group of experimental birds receiving both cyanobacterial biomass and lead. There was considerable accumulation of microcystins in the liver tissue of all cyanobacterial biomass exposed birds. There was a drop in haematocrit and haemoglobin concentrations in all lead exposed groups. Both single and combined exposures to cyanobacteria

Druh

D - Stať ve sborníku

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

sborník příspěvků XI. konference mladých věděckých pracovníků

ISBN

978-80-7305-068-9

ISSN

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e-ISSN

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Počet stran výsledku

3

Strana od-do

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Název nakladatele

Veterinární a farmaceutická univerzita Brno

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

3. 6. 2009

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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