Allenyloxime - A New Versatile Precursor for the Synthesis of Heterocycles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00048789" target="_blank" >RIV/00216224:14310/10:00048789 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Allenyloxime - A New Versatile Precursor for the Synthesis of Heterocycles

Popis výsledku v původním jazyce

We have developed a new methodology for synthesis of diverse heterocyclic compounds based on a simple starting material. Selected allenyloximes shoved high reactivity toward heterocyclizations when exposed to different reaction conditions. Cyclic nitrones bearing various functional groups at positions 2 and 5 were generated. Obtained products were isolated, fully characterized or served as key intermediates for further modification of nitrone skeleton in effective one-pot domino reactions. Additionally,a chemistry of selected cyclic products was explored. Prepared nitrones underwent 1,3-dipolar cycloadditions and with several reactive dipolarophiles formed corresponding products.

Název v anglickém jazyce

Allenyloxime - A New Versatile Precursor for the Synthesis of Heterocycles

Popis výsledku anglicky

We have developed a new methodology for synthesis of diverse heterocyclic compounds based on a simple starting material. Selected allenyloximes shoved high reactivity toward heterocyclizations when exposed to different reaction conditions. Cyclic nitrones bearing various functional groups at positions 2 and 5 were generated. Obtained products were isolated, fully characterized or served as key intermediates for further modification of nitrone skeleton in effective one-pot domino reactions. Additionally,a chemistry of selected cyclic products was explored. Prepared nitrones underwent 1,3-dipolar cycloadditions and with several reactive dipolarophiles formed corresponding products.

Druh

O - Ostatní výsledky

CEP obor

CC - Organická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/GA203%2F09%2F1345" target="_blank" >GA203/09/1345: Allenový synthon v přípravě heterocyklických sloučenin</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů