Nematode infection model for testing of innate immunity in Drosophila

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00049852" target="_blank" >RIV/00216224:14310/11:00049852 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Nematode infection model for testing of innate immunity in Drosophila

Popis výsledku v původním jazyce

Entomopathogenic nematodes (EPN?s) of the genera Heterorhabditis are obligate and lethal insect parasites. In recent years they have been used increasingly as biological control agents. Infective juveniles occur free living in the soil and are capable ofseeking out hosts and penetrate them through the cuticle or natural orifices. EPN?s are symbiotically associated with bacteria of the genera Photorhabdus. The bacterial symbionts are essential to kill the host (within 24-48 hours) and digest host tissues. The tripartite model (Drosophila, nematodes, bacteria) was recently established and used for determination of immune factors against nematode infection. Drosophila larvae are more resistant to nematode infection than Galleria mellonella (insect used for laboratory nematode rearing), but both can be used as natural infection model.

Název v anglickém jazyce

Nematode infection model for testing of innate immunity in Drosophila

Popis výsledku anglicky

Entomopathogenic nematodes (EPN?s) of the genera Heterorhabditis are obligate and lethal insect parasites. In recent years they have been used increasingly as biological control agents. Infective juveniles occur free living in the soil and are capable ofseeking out hosts and penetrate them through the cuticle or natural orifices. EPN?s are symbiotically associated with bacteria of the genera Photorhabdus. The bacterial symbionts are essential to kill the host (within 24-48 hours) and digest host tissues. The tripartite model (Drosophila, nematodes, bacteria) was recently established and used for determination of immune factors against nematode infection. Drosophila larvae are more resistant to nematode infection than Galleria mellonella (insect used for laboratory nematode rearing), but both can be used as natural infection model.

Druh

O - Ostatní výsledky

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

<a href="/cs/project/GP206%2F09%2FP470" target="_blank" >GP206/09/P470: Vliv inhibitorů biosyntézy eikosanoidů na imunitu zavíječe voskového Galleria mellonella</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů