Gold nanoparticles modified by thrombin binding aptamer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00054375" target="_blank" >RIV/00216224:14310/11:00054375 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Gold nanoparticles modified by thrombin binding aptamer

Popis výsledku v původním jazyce

In the last few decades nanotechnology has been bringing new possibilities for the construction of biosensors and development of new bioassays [1]. The greatest attention has been paid to gold nanoparticles (AuNPs) which, due to their good biocompatibility, conductivity and unique structural, electronic, magnetic, optical and catalytic properties, are very attractive materials for the construction of chemical sensors and biosensors [2,3]. For the study of proteins the construction of biosensors consistsin modified AuNPs anchored on the surface of electrodes, aptamer bonding to the protein studied [4]. The most intensively studied aptamer is a DNA 15-mer known as thrombin binding aptamer (TBA), which binds thrombin and inhibits its activity in the formation of a blood clot [5].

Název v anglickém jazyce

Gold nanoparticles modified by thrombin binding aptamer

Popis výsledku anglicky

In the last few decades nanotechnology has been bringing new possibilities for the construction of biosensors and development of new bioassays [1]. The greatest attention has been paid to gold nanoparticles (AuNPs) which, due to their good biocompatibility, conductivity and unique structural, electronic, magnetic, optical and catalytic properties, are very attractive materials for the construction of chemical sensors and biosensors [2,3]. For the study of proteins the construction of biosensors consistsin modified AuNPs anchored on the surface of electrodes, aptamer bonding to the protein studied [4]. The most intensively studied aptamer is a DNA 15-mer known as thrombin binding aptamer (TBA), which binds thrombin and inhibits its activity in the formation of a blood clot [5].

Druh

O - Ostatní výsledky

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/LC06035" target="_blank" >LC06035: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů