Electrochemical Behaviour of Apoferritin Encapsulating of Silver(I) Ions and Its Application for Treatment of Staphylococcus aureus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00060702" target="_blank" >RIV/00216224:14310/12:00060702 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26620/12:PU99009 RIV/62156489:43210/12:00189327 RIV/00159816:_____/12:00063530

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Electrochemical Behaviour of Apoferritin Encapsulating of Silver(I) Ions and Its Application for Treatment of Staphylococcus aureus

Popis výsledku v původním jazyce

Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for several difficult-to-treat infections in humans. Therefore, it is not surprising that other ways how to treat these bacteria are looked for. Silver(I) ions and silver nanoparticles exhibited the highest antimicrobial activity against MRSA but their transporting to the place of needs and in situ determination is an issue. The aim of this work was electrochemical determination of silver(I) ions using four types of modified carbon pasteelectrodes (CPEs) with different content of carbon nanoparticles. CPE made from expanded carbon was the most sensitive one. Therefore, we optimized the experimental conditions as time of accumulation 60 s, deposition potential 0.5 V and 0.2 M acetate buffer, pH = 5.0 to obtain detection limit (3 S/N) of 5 nM for silver(I) ions. Further, we studied the encapsulation of silver(I) ions into apoferritin as a possible way for transportation of these ions.

Název v anglickém jazyce

Electrochemical Behaviour of Apoferritin Encapsulating of Silver(I) Ions and Its Application for Treatment of Staphylococcus aureus

Popis výsledku anglicky

Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for several difficult-to-treat infections in humans. Therefore, it is not surprising that other ways how to treat these bacteria are looked for. Silver(I) ions and silver nanoparticles exhibited the highest antimicrobial activity against MRSA but their transporting to the place of needs and in situ determination is an issue. The aim of this work was electrochemical determination of silver(I) ions using four types of modified carbon pasteelectrodes (CPEs) with different content of carbon nanoparticles. CPE made from expanded carbon was the most sensitive one. Therefore, we optimized the experimental conditions as time of accumulation 60 s, deposition potential 0.5 V and 0.2 M acetate buffer, pH = 5.0 to obtain detection limit (3 S/N) of 5 nM for silver(I) ions. Further, we studied the encapsulation of silver(I) ions into apoferritin as a possible way for transportation of these ions.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Electrochemical Science

ISSN

1452-3981

e-ISSN

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Svazek periodika

7

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

RS - Srbská republika

Počet stran výsledku

18

Strana od-do

6378-6395

Kód UT WoS článku

000306399700051

EID výsledku v databázi Scopus

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