Study of metallothionein-quantum dots interactions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00075727" target="_blank" >RIV/00216224:14310/14:00075727 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62156489:43210/14:00228540 RIV/00216305:26620/14:PU112619

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.colsurfb.2014.03.013" target="_blank" >http://dx.doi.org/10.1016/j.colsurfb.2014.03.013</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.colsurfb.2014.03.013" target="_blank" >10.1016/j.colsurfb.2014.03.013</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Study of metallothionein-quantum dots interactions

Popis výsledku v původním jazyce

Nanoparticles have gained increasing interest in medical and in vivo applications. Metallothionein (MT) is well known as a maintainer of metal ions balance in intracellular space. This is due to high affinity of this protein to any reactive species including metals and reactive oxygen species. The purpose of this study was to determine the metallothionein-quantum dots interactions that were investigated by spectral and electrochemical techniques. CuS, CdS, PbS, and CdTe quantum dots (QDs) were analysed.The highest intensity was shown for CdTe, than for CdS measured by fluorescence. These results were supported by statistical analysis and considered as significant. Further, these interactions were analysed using gel electrophoresis, where MT aggregatesforming after interactions with QDs were detected. Using differential pulse voltammetry Brdicka reaction, QDs and MT were studied.

Název v anglickém jazyce

Study of metallothionein-quantum dots interactions

Popis výsledku anglicky

Nanoparticles have gained increasing interest in medical and in vivo applications. Metallothionein (MT) is well known as a maintainer of metal ions balance in intracellular space. This is due to high affinity of this protein to any reactive species including metals and reactive oxygen species. The purpose of this study was to determine the metallothionein-quantum dots interactions that were investigated by spectral and electrochemical techniques. CuS, CdS, PbS, and CdTe quantum dots (QDs) were analysed.The highest intensity was shown for CdTe, than for CdS measured by fluorescence. These results were supported by statistical analysis and considered as significant. Further, these interactions were analysed using gel electrophoresis, where MT aggregatesforming after interactions with QDs were detected. Using differential pulse voltammetry Brdicka reaction, QDs and MT were studied.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Colloids and Surfaces B: Biointerferences

ISSN

0927-7765

e-ISSN

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Svazek periodika

117

Číslo periodika v rámci svazku

May

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

4

Strana od-do

534-537

Kód UT WoS článku

000336018700070

EID výsledku v databázi Scopus

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