Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00081546" target="_blank" >RIV/00216224:14310/15:00081546 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S002196731501314X" target="_blank" >http://www.sciencedirect.com/science/article/pii/S002196731501314X</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chroma.2015.09.030" target="_blank" >10.1016/j.chroma.2015.09.030</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride

Popis výsledku v původním jazyce

The present study describes an effect of reaction condition of pre-column derivatization of alkylphenols (APs): bisphenol A (BPA), 4-tert-octylphenol (4-t-OP), 4-octylphenol (4-OP), 4-n-nonylphenol (4-n-NP), and isomers of 4-nonylphenol (iso-NP) with 5-(dimethylamino) naphthalene-1-sulfonyl chloride (dansyl chloride, DNSC) on their LC?ESI?MS/MS determination in water samples. Chemical derivatization improves the sensitivity and selectivity of LC?MS/MS analysis. In principle, alkylphenols can be analyzedby LC?MS/MS without derivatization. However, pre-column derivatization of APs increases the sensitivity up to 1000 times in comparison with the analysis of underivatized alkylphenols. Reaction conditions affecting formation of the DNSC-derivatives, suchas various solvent, reaction temperature, reaction time, DNSC concentration and pH values were tested.

Název v anglickém jazyce

Determination of alkylphenols in water samples using liquid chromatography-tandem mass spectrometry after pre-column derivatization with dansyl chloride

Popis výsledku anglicky

The present study describes an effect of reaction condition of pre-column derivatization of alkylphenols (APs): bisphenol A (BPA), 4-tert-octylphenol (4-t-OP), 4-octylphenol (4-OP), 4-n-nonylphenol (4-n-NP), and isomers of 4-nonylphenol (iso-NP) with 5-(dimethylamino) naphthalene-1-sulfonyl chloride (dansyl chloride, DNSC) on their LC?ESI?MS/MS determination in water samples. Chemical derivatization improves the sensitivity and selectivity of LC?MS/MS analysis. In principle, alkylphenols can be analyzedby LC?MS/MS without derivatization. However, pre-column derivatization of APs increases the sensitivity up to 1000 times in comparison with the analysis of underivatized alkylphenols. Reaction conditions affecting formation of the DNSC-derivatives, suchas various solvent, reaction temperature, reaction time, DNSC concentration and pH values were tested.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A

ISSN

0021-9673

e-ISSN

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Svazek periodika

1417

Číslo periodika v rámci svazku

OCTOBER

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

49-56

Kód UT WoS článku

000363080700006

EID výsledku v databázi Scopus

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