CalFitter 1.0

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F17%3A00100391" target="_blank" >RIV/00216224:14310/17:00100391 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

CalFitter 1.0

Popis výsledku v původním jazyce

Differential scanning calorimetry (DSC) is an invaluable tool for studying protein thermal denaturation. Currently, however, no software enabling complex analysis of the resulting thermograms in a user-friendly manner is available. To address this, we have developed MatLab-based software called CalFitter which allows fitting of DSC curves into 10 models of unfolding including different number of intermediates, reversible and irreversible transitions and their combination. Moreover, it allows simultaneous fitting of DSC scans together with re-heating traces collected after termination of the first run at different temperatures. CalFitter output can be exported to single excel file that includes quantitative description of unfolding model in terms of number of intermediates, energy parameters of each transition with statistical information and fraction of protein states calculated based on the model.

Název v anglickém jazyce

CalFitter 1.0

Popis výsledku anglicky

Differential scanning calorimetry (DSC) is an invaluable tool for studying protein thermal denaturation. Currently, however, no software enabling complex analysis of the resulting thermograms in a user-friendly manner is available. To address this, we have developed MatLab-based software called CalFitter which allows fitting of DSC curves into 10 models of unfolding including different number of intermediates, reversible and irreversible transitions and their combination. Moreover, it allows simultaneous fitting of DSC scans together with re-heating traces collected after termination of the first run at different temperatures. CalFitter output can be exported to single excel file that includes quantitative description of unfolding model in terms of number of intermediates, energy parameters of each transition with statistical information and fraction of protein states calculated based on the model.

Druh

R - Software

CEP obor

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OECD FORD obor

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Interní identifikační kód produktu

CalFitter 1.0

Technické parametry

licenční smlouva není

Ekonomické parametry

zvyšení zisku

IČO vlastníka výsledku

00216224

Název vlastníka

MU