First description of the emergence of Enterobacter asburiae producing IMI-2 carbapenemase in the Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F17%3A00108757" target="_blank" >RIV/00216224:14310/17:00108757 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/17:10365174 RIV/00064165:_____/17:10365174

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S221371651730187X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S221371651730187X?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jgar.2017.10.001" target="_blank" >10.1016/j.jgar.2017.10.001</a>

Jazyk výsledku

angličtina

Název v původním jazyce

First description of the emergence of Enterobacter asburiae producing IMI-2 carbapenemase in the Czech Republic

Popis výsledku v původním jazyce

The acquired class A carbapenemase IMI-1 was originally described in an Enterobacter cloacae isolated in a Californian hospital in 1984 [1]. Since their first description, IMI-type carbapenemases have occasionally been detected in Enterobacteriaceae from the USA, Europe, the Far East and South Africa. Here we report the case of an IMI-2-producing Enterobacter asburiae identified in the Czech Republic. In 2016, E. asburiae Easb-36567cz was recovered from a patient admitted to a Czech hospital. Easb-36567cz was isolated from a rectal swab during routine screening for carbapenemase-producing Enterobacteriaceae (CPE). Easb-36567cz was resistant to aminopenicillins, aminopenicillin/sulbactam combinations, second-generation cephalosporins, aztreonam, carbapenems and colistin but was susceptible to piperacillin/tazobactam, cefotaxime, ceftazidime and various non-beta-lactam antibiotics (Table 1). Carbapenemase production was hypothesised by a positive result in the matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) imipenem hydrolysis assay [2]. Easb-36567cz tested negative by the ethylene diamine tetra-acetic acid (EDTA)–meropenem test, whilst the respective boronic acid–meropenem combined-disk test appeared positive indicating production of a class A carbapenemase. PCR and sequencing showed that Easb-36567cz carried blaIMI-2 [3].

Název v anglickém jazyce

First description of the emergence of Enterobacter asburiae producing IMI-2 carbapenemase in the Czech Republic

Popis výsledku anglicky

The acquired class A carbapenemase IMI-1 was originally described in an Enterobacter cloacae isolated in a Californian hospital in 1984 [1]. Since their first description, IMI-type carbapenemases have occasionally been detected in Enterobacteriaceae from the USA, Europe, the Far East and South Africa. Here we report the case of an IMI-2-producing Enterobacter asburiae identified in the Czech Republic. In 2016, E. asburiae Easb-36567cz was recovered from a patient admitted to a Czech hospital. Easb-36567cz was isolated from a rectal swab during routine screening for carbapenemase-producing Enterobacteriaceae (CPE). Easb-36567cz was resistant to aminopenicillins, aminopenicillin/sulbactam combinations, second-generation cephalosporins, aztreonam, carbapenems and colistin but was susceptible to piperacillin/tazobactam, cefotaxime, ceftazidime and various non-beta-lactam antibiotics (Table 1). Carbapenemase production was hypothesised by a positive result in the matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) imipenem hydrolysis assay [2]. Easb-36567cz tested negative by the ethylene diamine tetra-acetic acid (EDTA)–meropenem test, whilst the respective boronic acid–meropenem combined-disk test appeared positive indicating production of a class A carbapenemase. PCR and sequencing showed that Easb-36567cz carried blaIMI-2 [3].

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30100 - Basic medicine

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Global Antimicrobial Resistance

ISSN

2213-7165

e-ISSN

2213-7173

Svazek periodika

11

Číslo periodika v rámci svazku

DEC

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

2

Strana od-do

98-99

Kód UT WoS článku

000416992000020

EID výsledku v databázi Scopus

2-s2.0-85032306295