Effect of intestinal microbiome, antibiotics, and probiotics in the prevention and management of ulcerative colitis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F22%3A00125081" target="_blank" >RIV/00216224:14310/22:00125081 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/B9780128237335000167" target="_blank" >https://www.sciencedirect.com/science/article/pii/B9780128237335000167</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/B978-0-12-823733-5.00016-7" target="_blank" >10.1016/B978-0-12-823733-5.00016-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of intestinal microbiome, antibiotics, and probiotics in the prevention and management of ulcerative colitis

Popis výsledku v původním jazyce

More and more people suffer from a variety of chronic inflammatory diseases, which are mainly caused by stress and a deteriorating environment. Chronic inflammatory bowel diseases are one of the most common such diseases. Their treatment is problematic and lengthy, and in fact, patients are never really cured. In addition, these diseases are associated with a number of other intestinal problems. The intestinal microbiome is a great help in the fight against these chronic diseases. This chapter summarizes current literature data on the role of microbiota in the development of human colon diseases. Special attention is paid to the involvement of sulfate- reducing bacteria in the development of ulcerative colitis. They are characterized by methods of molecular hydrogen metabolism by sulfate-reducing bacteria in the intestine. The influence and mechanism of action of the main product of metabolism of these microorganisms—hydrogen sulfide—on cells is described. The properties of antimicrobial drugs used in intestinal diseases are presented, and the importance of probiotics for the prevention and treatment of intestinal diseases is described.

Název v anglickém jazyce

Effect of intestinal microbiome, antibiotics, and probiotics in the prevention and management of ulcerative colitis

Popis výsledku anglicky

More and more people suffer from a variety of chronic inflammatory diseases, which are mainly caused by stress and a deteriorating environment. Chronic inflammatory bowel diseases are one of the most common such diseases. Their treatment is problematic and lengthy, and in fact, patients are never really cured. In addition, these diseases are associated with a number of other intestinal problems. The intestinal microbiome is a great help in the fight against these chronic diseases. This chapter summarizes current literature data on the role of microbiota in the development of human colon diseases. Special attention is paid to the involvement of sulfate- reducing bacteria in the development of ulcerative colitis. They are characterized by methods of molecular hydrogen metabolism by sulfate-reducing bacteria in the intestine. The influence and mechanism of action of the main product of metabolism of these microorganisms—hydrogen sulfide—on cells is described. The properties of antimicrobial drugs used in intestinal diseases are presented, and the importance of probiotics for the prevention and treatment of intestinal diseases is described.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Probiotics in the Prevention and Management of Human Diseases : A Scientific Perspective

ISBN

9780128237335

Počet stran výsledku

34

Strana od-do

59-92

Počet stran knihy

509

Název nakladatele

Elsevier

Místo vydání

Cambridge

Kód UT WoS kapitoly

—