Variability of 27 Autosomal STR Loci for the Population of the Republic of Belarus Based on the Mass Parallel Sequencing Data

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F23%3A00136439" target="_blank" >RIV/00216224:14310/23:00136439 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1134/S1022795423030079" target="_blank" >https://link.springer.com/article/10.1134/S1022795423030079</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1134/S1022795423030079" target="_blank" >10.1134/S1022795423030079</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Variability of 27 Autosomal STR Loci for the Population of the Republic of Belarus Based on the Mass Parallel Sequencing Data

Popis výsledku v původním jazyce

The variability of 27 autosomal STR loci of the ForenSeq DNA Signature Prep Kit (Illumina) commercial panel was studied using the technique of massively parallel sequencing (MPS) in 733 unrelated individuals representing the population of the Republic of Belarus, as well as a population base of MPS allele frequencies for forensic probabilistic calculations in human identification and paternity testing was evaluated. The agreement between genotypes obtained by MPS and capillary electrophoresis (CE) was 99.96%. The number of MPS alleles increased more than two times for eight loci (D12S391, D21S11, D2S1338, vWA, D3S1358, D8S1179, D13S317, and D9S1122). Thirteen alleles detected were not included in the STRSeq BioProject catalog of the international online database STRbase 2.0. The random match probability of 27-locus MPS profiles decreased from 1.43 x 10(-31) to 2.89 x 10(-35), and the combined paternity index increased from 2.08 x 10(10) to 3.25 x 10(12) compared to CE data.

Název v anglickém jazyce

Variability of 27 Autosomal STR Loci for the Population of the Republic of Belarus Based on the Mass Parallel Sequencing Data

Popis výsledku anglicky

The variability of 27 autosomal STR loci of the ForenSeq DNA Signature Prep Kit (Illumina) commercial panel was studied using the technique of massively parallel sequencing (MPS) in 733 unrelated individuals representing the population of the Republic of Belarus, as well as a population base of MPS allele frequencies for forensic probabilistic calculations in human identification and paternity testing was evaluated. The agreement between genotypes obtained by MPS and capillary electrophoresis (CE) was 99.96%. The number of MPS alleles increased more than two times for eight loci (D12S391, D21S11, D2S1338, vWA, D3S1358, D8S1179, D13S317, and D9S1122). Thirteen alleles detected were not included in the STRSeq BioProject catalog of the international online database STRbase 2.0. The random match probability of 27-locus MPS profiles decreased from 1.43 x 10(-31) to 2.89 x 10(-35), and the combined paternity index increased from 2.08 x 10(10) to 3.25 x 10(12) compared to CE data.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10603 - Genetics and heredity (medical genetics to be 3)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Russian Journal of Genetics

ISSN

1022-7954

e-ISSN

1608-3369

Svazek periodika

59

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

307-316

Kód UT WoS článku

001094604300010

EID výsledku v databázi Scopus

2-s2.0-85171296595