Study of the gene expression in malignant diseases by cDNA microarray technology

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F03%3A00009005" target="_blank" >RIV/00216224:14330/03:00009005 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14330/03:00008566

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Study of the gene expression in malignant diseases by cDNA microarray technology

Popis výsledku v původním jazyce

At the present time, a number of various diseases increases and thereby also increases the necessity of new therapeutic methods and new approaches to research. In last decade, many new technologies have been evolving, among others the technology called cDNA microarrays. This technology enables the detection of global gene-expression profiles, the identification of new molecular cancer markers. It makes possible the comparison of gene-expression profiles of various cancer tumors and cell lines under different environmental stress conditions. cDNA microarrays consist of hundreds or thousands spots with different cDNA sequences (resp. oligonucleotide sequence strands) organized in grids and they can contain more than 20,000 specific sequences on a singleslide. This technology is based on process of hybridization between immobilized cDNAs (oligonucleotides sequences) and reverse-transcribed cDNA from sample of total RNA. We used cDNA microarray technology to study gene expression profiles

Název v anglickém jazyce

Study of the gene expression in malignant diseases by cDNA microarray technology

Popis výsledku anglicky

At the present time, a number of various diseases increases and thereby also increases the necessity of new therapeutic methods and new approaches to research. In last decade, many new technologies have been evolving, among others the technology called cDNA microarrays. This technology enables the detection of global gene-expression profiles, the identification of new molecular cancer markers. It makes possible the comparison of gene-expression profiles of various cancer tumors and cell lines under different environmental stress conditions. cDNA microarrays consist of hundreds or thousands spots with different cDNA sequences (resp. oligonucleotide sequence strands) organized in grids and they can contain more than 20,000 specific sequences on a singleslide. This technology is based on process of hybridization between immobilized cDNAs (oligonucleotides sequences) and reverse-transcribed cDNA from sample of total RNA. We used cDNA microarray technology to study gene expression profiles

Druh

D - Stať ve sborníku

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

<a href="/cs/project/NC6987" target="_blank" >NC6987: Epigeneticky kontrolované změny exprese genů u nádorových onemocnění</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2003

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Biophysics of the Genome

ISBN

80-210-3226-X

ISSN

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e-ISSN

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Počet stran výsledku

5

Strana od-do

25-29

Název nakladatele

Masaryk University

Místo vydání

Brno

Místo konání akce

Hlohovec,Czech Republic

Datum konání akce

1. 1. 2003

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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