cDNA microarray technologie jako nástroj k lepšímu pochopení progrese maligních onemocnění

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F05%3A00013836" target="_blank" >RIV/00216224:14330/05:00013836 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

cDNA Microarray Technology as a Tool for Better Understanding of Progress of Malignant Diseases

Popis výsledku v původním jazyce

Array technologies have made it straightforward to monitor the expression pattern of thousands of genes simultaneously. We develop new tools, not only for the analysis of gene expression, but also for better diagnostics of various types of malignances inour laboratory. The development of better diagnostic techniques requires different approach in the evaluation of obtained microarray data. The first step of microarray data processing is precise image analysis of the data obtained using scanner. The software developed in our laboratory was used. The grid was fully-automatically set up for each image and the alignment to the array of spots was checked. This software also contains normalisation methods. We learned the differences in agnostics of varioustypes of malignances and therefore our results represent new possibilities how to validate microarray data. Human 19,008 cDNA microarrays were used to analyze gene expression profiles of 18 patients with colorectal cancer against normal c

Název v anglickém jazyce

cDNA Microarray Technology as a Tool for Better Understanding of Progress of Malignant Diseases

Popis výsledku anglicky

Array technologies have made it straightforward to monitor the expression pattern of thousands of genes simultaneously. We develop new tools, not only for the analysis of gene expression, but also for better diagnostics of various types of malignances inour laboratory. The development of better diagnostic techniques requires different approach in the evaluation of obtained microarray data. The first step of microarray data processing is precise image analysis of the data obtained using scanner. The software developed in our laboratory was used. The grid was fully-automatically set up for each image and the alignment to the array of spots was checked. This software also contains normalisation methods. We learned the differences in agnostics of varioustypes of malignances and therefore our results represent new possibilities how to validate microarray data. Human 19,008 cDNA microarrays were used to analyze gene expression profiles of 18 patients with colorectal cancer against normal c

Druh

D - Stať ve sborníku

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Prague Post Genome Technology Workshop

ISBN

80-01-03239-6

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

69-72

Název nakladatele

Czech Pattern Recognition Society

Místo vydání

Prague, Czech Republic

Místo konání akce

Prague, Czech Republic

Datum konání akce

6. 6. 2005

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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