Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F09%3A00034932" target="_blank" >RIV/00216224:14330/09:00034932 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry

Popis výsledku v původním jazyce

Image cytometry still faces the problem of the quality of cell image analysis results. Degradations caused by cell preparation, optics and electronics considerably affect most 2D and 3D cell image data acquired using optical microscopy. That is why imageprocessing algorithms applied to these data typically offer imprecise and unreliable results. We have created a toolbox that can generate 3D digital phantoms of specific cellular components along with their corresponding images degraded by specific optics and electronics. The user can then apply image analysis methods to such simulated image data. The analysis results can be compared with ground truth derived from input object digital phantoms. In this way, image analysis methods can be compared to each other and their quality can be computed. We have also evaluated the plausibility of the synthetic images, measured by their similarity to real image data.

Název v anglickém jazyce

Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry

Popis výsledku anglicky

Image cytometry still faces the problem of the quality of cell image analysis results. Degradations caused by cell preparation, optics and electronics considerably affect most 2D and 3D cell image data acquired using optical microscopy. That is why imageprocessing algorithms applied to these data typically offer imprecise and unreliable results. We have created a toolbox that can generate 3D digital phantoms of specific cellular components along with their corresponding images degraded by specific optics and electronics. The user can then apply image analysis methods to such simulated image data. The analysis results can be compared with ground truth derived from input object digital phantoms. In this way, image analysis methods can be compared to each other and their quality can be computed. We have also evaluated the plausibility of the synthetic images, measured by their similarity to real image data.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JD - Využití počítačů, robotika a její aplikace

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cytometry Part A

ISSN

1552-4922

e-ISSN

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Svazek periodika

75A

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

16

Strana od-do

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Kód UT WoS článku

000266470100003

EID výsledku v databázi Scopus

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