Palladium(II) complexes of dithiocarbamic acids: synthesis, characterization, crystal structure and DNA binding study
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00079730" target="_blank" >RIV/00216224:14740/12:00079730 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1007/s11243-011-9569-9" target="_blank" >http://dx.doi.org/10.1007/s11243-011-9569-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11243-011-9569-9" target="_blank" >10.1007/s11243-011-9569-9</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Palladium(II) complexes of dithiocarbamic acids: synthesis, characterization, crystal structure and DNA binding study
Popis výsledku v původním jazyce
A series of distorted square planar palladium(II) complexes with dithiocarbamic acids of general formula [Pd(L)(2)], where L = 4-methylpiperazine-l-carbodithioic acid anion, morpholine-4-carbodithioic acid anion or 4-benzylpiperidine-l-carbodithioic acidanion for complexes 1a, 1b and 1c, respectively, have been synthesized. The complexes were characterized by physicochemical and spectroscopic methods; in addition, the structure of complex 1a was characterized by single crystal X-ray crystallography. The interaction of these palladium complexes with CT-DNA was investigated with the help of absorption and emission spectroscopy. The association constant K-b was deduced from the absorption spectra, while the number of binding sites and the binding constant were calculated from the fluorescence quenching data. The results suggest an intercalative interaction of the complexes with CT-DNA.
Název v anglickém jazyce
Palladium(II) complexes of dithiocarbamic acids: synthesis, characterization, crystal structure and DNA binding study
Popis výsledku anglicky
A series of distorted square planar palladium(II) complexes with dithiocarbamic acids of general formula [Pd(L)(2)], where L = 4-methylpiperazine-l-carbodithioic acid anion, morpholine-4-carbodithioic acid anion or 4-benzylpiperidine-l-carbodithioic acidanion for complexes 1a, 1b and 1c, respectively, have been synthesized. The complexes were characterized by physicochemical and spectroscopic methods; in addition, the structure of complex 1a was characterized by single crystal X-ray crystallography. The interaction of these palladium complexes with CT-DNA was investigated with the help of absorption and emission spectroscopy. The association constant K-b was deduced from the absorption spectra, while the number of binding sites and the binding constant were calculated from the fluorescence quenching data. The results suggest an intercalative interaction of the complexes with CT-DNA.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CA - Anorganická chemie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Transition Metal Chemistry
ISSN
0340-4285
e-ISSN
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Svazek periodika
37
Číslo periodika v rámci svazku
2
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
7
Strana od-do
155-161
Kód UT WoS článku
000302376000005
EID výsledku v databázi Scopus
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