Antagonism of Adenosine A1 or A2A Receptors Amplifies the Effects of MDMA on Glial Activation in the Mouse Brain: Relevance to Caffeine?MDMA Interactions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F14%3A00080044" target="_blank" >RIV/00216224:14740/14:00080044 - isvavai.cz</a>

Výsledek na webu

<a href="http://online.liebertpub.com/doi/pdfplus/10.1089/jcr.2014.0006" target="_blank" >http://online.liebertpub.com/doi/pdfplus/10.1089/jcr.2014.0006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1089/jcr.2014.0006" target="_blank" >10.1089/jcr.2014.0006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Antagonism of Adenosine A1 or A2A Receptors Amplifies the Effects of MDMA on Glial Activation in the Mouse Brain: Relevance to Caffeine?MDMA Interactions

Popis výsledku v původním jazyce

3,4-Methylendioxymethamphetamine (MDMA, "ecstasy") is a recreational drug very popular in settings such as dance parties and raves.1 MDMA is usually sold on the illegal market as tablets which, besides the drug itself, often contain several impurities, including other psychoactive substances.2 Caffeine is one of the most common of these contaminants,3?5 and this suggests that the unintentional combined consumption of caffeine and MDMA is very likely in people who take this amphetamine-related drug. In addition, the habit of consuming caffeinated beverages together with psychostimulants, to attenuate the endof- dose side effects of these drugs, has increased since the introduction of the so-called energy drinks. Because of this, the possible pharmacological interactions between MDMA and caffeine deserve full consideration.

Název v anglickém jazyce

Antagonism of Adenosine A1 or A2A Receptors Amplifies the Effects of MDMA on Glial Activation in the Mouse Brain: Relevance to Caffeine?MDMA Interactions

Popis výsledku anglicky

3,4-Methylendioxymethamphetamine (MDMA, "ecstasy") is a recreational drug very popular in settings such as dance parties and raves.1 MDMA is usually sold on the illegal market as tablets which, besides the drug itself, often contain several impurities, including other psychoactive substances.2 Caffeine is one of the most common of these contaminants,3?5 and this suggests that the unintentional combined consumption of caffeine and MDMA is very likely in people who take this amphetamine-related drug. In addition, the habit of consuming caffeinated beverages together with psychostimulants, to attenuate the endof- dose side effects of these drugs, has increased since the introduction of the so-called energy drinks. Because of this, the possible pharmacological interactions between MDMA and caffeine deserve full consideration.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/EE2.3.30.0009" target="_blank" >EE2.3.30.0009: Zaměstnáním čerstvých absolventů doktorského studia k vědecké excelenci</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Caffeine Research

ISSN

2156-5783

e-ISSN

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Svazek periodika

4

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

41-47

Kód UT WoS článku

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EID výsledku v databázi Scopus

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