Chromatin dynamics of plant telomeres and ribosomal genes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00080972" target="_blank" >RIV/00216224:14740/15:00080972 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081707:_____/15:00446224

Výsledek na webu

<a href="http://onlinelibrary.wiley.com/doi/10.1111/tpj.12822/epdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/tpj.12822/epdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/tpj.12822" target="_blank" >10.1111/tpj.12822</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chromatin dynamics of plant telomeres and ribosomal genes

Popis výsledku v původním jazyce

Telomeres and genes encoding 45S ribosomal RNA (rDNA) are frequently located adjacent to each other on eukaryotic chromosomes. Although their primary roles are different, they show striking similarities with respect to their features and additional functions. Both genome domains have remarkably dynamic chromatin structures. Both are hypersensitive to dysfunctional histone chaperones, responding at the genomic and epigenomic levels. Both generate non-coding transcripts that, in addition to their epigenetic roles, may induce gross chromosomal rearrangements. Both give rise to chromosomal fragile sites, as their replication is intrinsically problematic. However, at the same time, both are essential for maintenance of genomic stability and integrity. Herewe discuss the structural and functional inter-connectivity of telomeres and rDNA, with a focus on recent results obtained in plants.

Název v anglickém jazyce

Chromatin dynamics of plant telomeres and ribosomal genes

Popis výsledku anglicky

Telomeres and genes encoding 45S ribosomal RNA (rDNA) are frequently located adjacent to each other on eukaryotic chromosomes. Although their primary roles are different, they show striking similarities with respect to their features and additional functions. Both genome domains have remarkably dynamic chromatin structures. Both are hypersensitive to dysfunctional histone chaperones, responding at the genomic and epigenomic levels. Both generate non-coding transcripts that, in addition to their epigenetic roles, may induce gross chromosomal rearrangements. Both give rise to chromosomal fragile sites, as their replication is intrinsically problematic. However, at the same time, both are essential for maintenance of genomic stability and integrity. Herewe discuss the structural and functional inter-connectivity of telomeres and rDNA, with a focus on recent results obtained in plants.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

The Plant Journal

ISSN

0960-7412

e-ISSN

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Svazek periodika

83

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

20

Strana od-do

18-37

Kód UT WoS článku

000357615300003

EID výsledku v databázi Scopus

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