Nanostructured gold electrodes for determination of glucose in blood

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00083973" target="_blank" >RIV/00216224:14740/15:00083973 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081715:_____/15:00450523

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Nanostructured gold electrodes for determination of glucose in blood

Popis výsledku v původním jazyce

Fast and sensitive devices for monitoring of glucose are crucial in today?s medicine. Most of the commercial glucometers are currently based on enzymatic catalysis which provides reasonable sensitivity but has a drawback in limited enzyme stability. Withthe development of novel surfaces, new generation of non-enzymatic sensors characterized by high sensitivity and stability is emerging. In this work, gelatin-templated nanostructured gold electrodes were developed and applied for non-enzymatic glucose determination. The analysis was done by direct electrochemical oxidation during cyclic voltammetry and amperometry with the limit of detection at 1.3 ?M. The ability to detect physiological levels glucose in presence of interferents was demonstrated on deproteinized human blood serum.

Název v anglickém jazyce

Nanostructured gold electrodes for determination of glucose in blood

Popis výsledku anglicky

Fast and sensitive devices for monitoring of glucose are crucial in today?s medicine. Most of the commercial glucometers are currently based on enzymatic catalysis which provides reasonable sensitivity but has a drawback in limited enzyme stability. Withthe development of novel surfaces, new generation of non-enzymatic sensors characterized by high sensitivity and stability is emerging. In this work, gelatin-templated nanostructured gold electrodes were developed and applied for non-enzymatic glucose determination. The analysis was done by direct electrochemical oxidation during cyclic voltammetry and amperometry with the limit of detection at 1.3 ?M. The ability to detect physiological levels glucose in presence of interferents was demonstrated on deproteinized human blood serum.

Druh

D - Stať ve sborníku

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

CECE 2015

ISBN

9788090495937

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

54-57

Název nakladatele

Institute of Analytical Chemistry of the CAS, v. v. i.

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

21. 9. 2015

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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