tcR: an R package for T cell receptor repertoire advanced data analysis
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00085151" target="_blank" >RIV/00216224:14740/15:00085151 - isvavai.cz</a>
Výsledek na webu
<a href="http://download.springer.com/static/pdf/403/art%253A10.1186%252Fs12859-015-0613-1.pdf?originUrl=http%3A%2F%2Fbmcbioinformatics.biomedcentral.com%2Farticle%2F10.1186%2Fs12859-015-0613-1&token2=exp=1452494593~acl=%2Fstatic%2Fpdf%2F403%2Fart%25253A10.1186%2" target="_blank" >http://download.springer.com/static/pdf/403/art%253A10.1186%252Fs12859-015-0613-1.pdf?originUrl=http%3A%2F%2Fbmcbioinformatics.biomedcentral.com%2Farticle%2F10.1186%2Fs12859-015-0613-1&token2=exp=1452494593~acl=%2Fstatic%2Fpdf%2F403%2Fart%25253A10.1186%2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12859-015-0613-1" target="_blank" >10.1186/s12859-015-0613-1</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
tcR: an R package for T cell receptor repertoire advanced data analysis
Popis výsledku v původním jazyce
Background The Immunoglobulins (IG) and the T cell receptors (TR) play the key role in antigen recognition during the adaptive immune response. Recent progress in next-generation sequencing technologies has provided an opportunity for the deep T cell receptor repertoire profiling. However, a specialised software is required for the rational analysis of massive data generated by next-generation sequencing. Results Here we introduce tcR, a new R package, representing a platform for the advanced analysis of T cell receptor repertoires, which includes diversity measures, shared T cell receptor sequences identification, gene usage statistics computation and other widely used methods. The tool has proven its utility in recent research studies. Conclusions tcR is an R package for the advanced analysis of T cell receptor repertoires after primary TR sequences extraction from raw sequencing reads. The stable version can be directly installed from The Comprehensive R Archive Network (http://cran
Název v anglickém jazyce
tcR: an R package for T cell receptor repertoire advanced data analysis
Popis výsledku anglicky
Background The Immunoglobulins (IG) and the T cell receptors (TR) play the key role in antigen recognition during the adaptive immune response. Recent progress in next-generation sequencing technologies has provided an opportunity for the deep T cell receptor repertoire profiling. However, a specialised software is required for the rational analysis of massive data generated by next-generation sequencing. Results Here we introduce tcR, a new R package, representing a platform for the advanced analysis of T cell receptor repertoires, which includes diversity measures, shared T cell receptor sequences identification, gene usage statistics computation and other widely used methods. The tool has proven its utility in recent research studies. Conclusions tcR is an R package for the advanced analysis of T cell receptor repertoires after primary TR sequences extraction from raw sequencing reads. The stable version can be directly installed from The Comprehensive R Archive Network (http://cran
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CE - Biochemie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
BMC Bioinformatics
ISSN
1471-2105
e-ISSN
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Svazek periodika
16
Číslo periodika v rámci svazku
May
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
5
Strana od-do
"nestránkováno"
Kód UT WoS článku
000355072600001
EID výsledku v databázi Scopus
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