Syntéza nových substituovaných 5-methyl-3,5-difenylimidazolidin-2,4-dionů ze substituovaných 1-(1-kyanethyl-1-fenyl)-3-phenylmočovin

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F05%3A00003237" target="_blank" >RIV/00216275:25310/05:00003237 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Synthesis of new substituted 5-methyl-3,5-diphenylimidazolidine-2,4-diones from substituted 1-(1-cyanoethyl-1-phenyl)-3-phenylureas

Popis výsledku v původním jazyce

The reaction of substituted phenyl isocyanates with 2-amino-2-phenylpropanenitrile and 2-amino-2-(4-nitrophenyl)propanenitrile has been used to prepare substituted 1-(1-cyanoethyl-1-phenyl)-3-phenylureas. In anhydrous phosphoric acid the first products to be formed from 1-(1-cyanoethyl-1-phenyl)-3-phenylureas are phosphates of 4-methyl-4-phenyl-2-phenylimino-5-imino-4,5-dihydro-1,3-oxazoles, which on subsequent hydrolysis give the respective ureidocarboxylic acids. On prolongation of the reaction time,the phosphates of 4-methyl-4-phenyl-2-phenylimino-5-imino-4,5-dihydro-1,3-oxazoles rearrange to give phosphates of 5-methyl-4-imino-3,5-diphenylimidazolidin-2-ones, and these are subsequently hydrolysed to the respective substituted 5-methyl-3,5-diphenylimidazolidin-2,4-diones. The ureidocarboxylic acids were also prepared by alkaline hydrolysis of 5-methyl-3,5-diphenylimidazolidin-2,4-diones. The 5-methyl-3,5-diphenylimidazolidin-2,4-diones and ureidocarboxylic acids were characterised

Název v anglickém jazyce

Synthesis of new substituted 5-methyl-3,5-diphenylimidazolidine-2,4-diones from substituted 1-(1-cyanoethyl-1-phenyl)-3-phenylureas

Popis výsledku anglicky

The reaction of substituted phenyl isocyanates with 2-amino-2-phenylpropanenitrile and 2-amino-2-(4-nitrophenyl)propanenitrile has been used to prepare substituted 1-(1-cyanoethyl-1-phenyl)-3-phenylureas. In anhydrous phosphoric acid the first products to be formed from 1-(1-cyanoethyl-1-phenyl)-3-phenylureas are phosphates of 4-methyl-4-phenyl-2-phenylimino-5-imino-4,5-dihydro-1,3-oxazoles, which on subsequent hydrolysis give the respective ureidocarboxylic acids. On prolongation of the reaction time,the phosphates of 4-methyl-4-phenyl-2-phenylimino-5-imino-4,5-dihydro-1,3-oxazoles rearrange to give phosphates of 5-methyl-4-imino-3,5-diphenylimidazolidin-2-ones, and these are subsequently hydrolysed to the respective substituted 5-methyl-3,5-diphenylimidazolidin-2,4-diones. The ureidocarboxylic acids were also prepared by alkaline hydrolysis of 5-methyl-3,5-diphenylimidazolidin-2,4-diones. The 5-methyl-3,5-diphenylimidazolidin-2,4-diones and ureidocarboxylic acids were characterised

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CC - Organická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/GA203%2F04%2F0646" target="_blank" >GA203/04/0646: Nové ligandy a komplexy mono- a bis(imidazolyl)pyridinů: Syntéza, charakterizace, vlastnosti</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Heterocyclic Chemistry

ISSN

0022-152X

e-ISSN

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Svazek periodika

42

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

899-906

Kód UT WoS článku

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EID výsledku v databázi Scopus

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