Synthesis of esters derived from 2,3,4,6-tetra-O-acetyl-1-[4-(2-hydroxyethyl)-1H-1,2,3-triazol-1-yl]-beta-D-glucopyranose

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896179" target="_blank" >RIV/00216275:25310/13:39896179 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.5155/eurjchem.4.1.64-69.735" target="_blank" >http://dx.doi.org/10.5155/eurjchem.4.1.64-69.735</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5155/eurjchem.4.1.64-69.735" target="_blank" >10.5155/eurjchem.4.1.64-69.735</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Synthesis of esters derived from 2,3,4,6-tetra-O-acetyl-1-[4-(2-hydroxyethyl)-1H-1,2,3-triazol-1-yl]-beta-D-glucopyranose

Popis výsledku v původním jazyce

2,3,4,6-Tetra-O-acetyl-1-[4-(2-hydroxyethyl)- 1H-1,2,3-triazol-1-yl]-beta-D-glucopyranose was prepared and reacted with several acids, either commercially available or prepared. These included, aliphatic or aromatic acids (phenylacetic acid derivatives,benzoic derivatives), palmitic acid and the protected amino acids N-(benzyloxycarbonyl)glycine and N-(tert- butyloxycarbonyl)phenylalanine. Two other acids, 2-(3-bromopropoxy)benzoic acid and 2- (5-bromopentoxy)benzoic acid (analogues of salicylic acid were synthesized), whose preparation is also described in this work. The esterification was performed either with N,N'- dicyclohexylcarbodiimide (DCC)/4-dimethylaminopyridine (DMAP) or by reacting the acyl chlorides with the alcohol in the presence of triethylamine. The products were isolated in fair yields and fully characterized by the usual analytical techniques.

Název v anglickém jazyce

Synthesis of esters derived from 2,3,4,6-tetra-O-acetyl-1-[4-(2-hydroxyethyl)-1H-1,2,3-triazol-1-yl]-beta-D-glucopyranose

Popis výsledku anglicky

2,3,4,6-Tetra-O-acetyl-1-[4-(2-hydroxyethyl)- 1H-1,2,3-triazol-1-yl]-beta-D-glucopyranose was prepared and reacted with several acids, either commercially available or prepared. These included, aliphatic or aromatic acids (phenylacetic acid derivatives,benzoic derivatives), palmitic acid and the protected amino acids N-(benzyloxycarbonyl)glycine and N-(tert- butyloxycarbonyl)phenylalanine. Two other acids, 2-(3-bromopropoxy)benzoic acid and 2- (5-bromopentoxy)benzoic acid (analogues of salicylic acid were synthesized), whose preparation is also described in this work. The esterification was performed either with N,N'- dicyclohexylcarbodiimide (DCC)/4-dimethylaminopyridine (DMAP) or by reacting the acyl chlorides with the alcohol in the presence of triethylamine. The products were isolated in fair yields and fully characterized by the usual analytical techniques.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CC - Organická chemie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Chemistry

ISSN

2153-2249

e-ISSN

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Svazek periodika

4

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

64-69

Kód UT WoS článku

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EID výsledku v databázi Scopus

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