Determination and Detailed Mechanism Study of Antiviral Drug Fosamprenavir Using Carbon Paste Electrode in the Presence of Triton X-100

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896534" target="_blank" >RIV/00216275:25310/13:39896534 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0013468613013698" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0013468613013698</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.electacta.2013.07.100" target="_blank" >10.1016/j.electacta.2013.07.100</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Determination and Detailed Mechanism Study of Antiviral Drug Fosamprenavir Using Carbon Paste Electrode in the Presence of Triton X-100

Popis výsledku v původním jazyce

The detailed electrochemical oxidation and selective determination of fosamprenavir were studied in aqueous-alcohol medium at a carbon paste electrode. Electrochemical behavior of fosamprenavir was investigated as details by different electrochemical techniques in the absence and presence of Triton X-100. The electrochemical mechanism was also carried out and aromatic amine part of the molecule was found to be involved in electrochemical oxidation of fosamprenavir. The oxidized form takes part in hydrolysis; the products are also electroactive and participate in redox reaction. Voltammetric studies were realized between pH 1.0 and 12.0. In the presence of Triton X-100, the signal increased almost 5 times. The promising analytical performance was obtained with developed method. A systematic study of the experimental parameters such as pH, scan rate, accumulation potential and accumulation time that affect the square wave stripping response was carried out and the optimized experimental

Název v anglickém jazyce

Determination and Detailed Mechanism Study of Antiviral Drug Fosamprenavir Using Carbon Paste Electrode in the Presence of Triton X-100

Popis výsledku anglicky

The detailed electrochemical oxidation and selective determination of fosamprenavir were studied in aqueous-alcohol medium at a carbon paste electrode. Electrochemical behavior of fosamprenavir was investigated as details by different electrochemical techniques in the absence and presence of Triton X-100. The electrochemical mechanism was also carried out and aromatic amine part of the molecule was found to be involved in electrochemical oxidation of fosamprenavir. The oxidized form takes part in hydrolysis; the products are also electroactive and participate in redox reaction. Voltammetric studies were realized between pH 1.0 and 12.0. In the presence of Triton X-100, the signal increased almost 5 times. The promising analytical performance was obtained with developed method. A systematic study of the experimental parameters such as pH, scan rate, accumulation potential and accumulation time that affect the square wave stripping response was carried out and the optimized experimental

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CG - Elektrochemie

OECD FORD obor

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Projekt

<a href="/cs/project/EE2.3.30.0021" target="_blank" >EE2.3.30.0021: Posílení excelentních týmů výzkumu a vývoje na Univerzitě Pardubice</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electrochimica Acta

ISSN

0013-4686

e-ISSN

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Svazek periodika

109

Číslo periodika v rámci svazku

říjen

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

381-388

Kód UT WoS článku

000328006300054

EID výsledku v databázi Scopus

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