Polystyrene copolymer-supported by substituted (1R,2R)-1,2-diphenylethane-1,2-diamine-copper(II) complexes: recyclable catalyst for the asymmetric Henry reaction
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F14%3A39897793" target="_blank" >RIV/00216275:25310/14:39897793 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.tetasy.2014.04.004" target="_blank" >http://dx.doi.org/10.1016/j.tetasy.2014.04.004</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.tetasy.2014.04.004" target="_blank" >10.1016/j.tetasy.2014.04.004</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Polystyrene copolymer-supported by substituted (1R,2R)-1,2-diphenylethane-1,2-diamine-copper(II) complexes: recyclable catalyst for the asymmetric Henry reaction
Popis výsledku v původním jazyce
Herein described the preparation of swelling pearl-like copolymer styrene-4-vinylbenzyl chloride crosslinked by means of tetra(ethylene glycol)-bis(4-vinylbenzyl)ether (200-800 mým). The pearl-like polymer was used to anchor (1R,2R)-1-amino-2-(2,3-dihydro-1H-isoindole-2-yl)-1,2-diphenylethane by a covalent bond; the product was subsequently transformed into the corresponding complex with Cu(II) acetate. The synthesized catalyst was used for the catalysis of the Henry reaction of functionalized aldehydeswith nitromethane in ethanol. The reactions proceeded in a polymeric matrix of the swelling catalyst at a rate comparable with the rates of reactions in a homogeneous medium. The corresponding functionalized 2-nitroethanols were formed in quantitative yields (20 °C, 24 h) with enantiomeric excess values of up to 96%. The catalyst was recycled five times without losing its effectiveness with regard to the yield and enantioselectivity; only a partial mechanical degradation of the polymeri
Název v anglickém jazyce
Polystyrene copolymer-supported by substituted (1R,2R)-1,2-diphenylethane-1,2-diamine-copper(II) complexes: recyclable catalyst for the asymmetric Henry reaction
Popis výsledku anglicky
Herein described the preparation of swelling pearl-like copolymer styrene-4-vinylbenzyl chloride crosslinked by means of tetra(ethylene glycol)-bis(4-vinylbenzyl)ether (200-800 mým). The pearl-like polymer was used to anchor (1R,2R)-1-amino-2-(2,3-dihydro-1H-isoindole-2-yl)-1,2-diphenylethane by a covalent bond; the product was subsequently transformed into the corresponding complex with Cu(II) acetate. The synthesized catalyst was used for the catalysis of the Henry reaction of functionalized aldehydeswith nitromethane in ethanol. The reactions proceeded in a polymeric matrix of the swelling catalyst at a rate comparable with the rates of reactions in a homogeneous medium. The corresponding functionalized 2-nitroethanols were formed in quantitative yields (20 °C, 24 h) with enantiomeric excess values of up to 96%. The catalyst was recycled five times without losing its effectiveness with regard to the yield and enantioselectivity; only a partial mechanical degradation of the polymeri
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CC - Organická chemie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GA14-00925S" target="_blank" >GA14-00925S: Imobilizované enantioselektivní katalyzátory</a><br>
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Tetrahedron Asymmetry
ISSN
0957-4166
e-ISSN
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Svazek periodika
25
Číslo periodika v rámci svazku
9
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
6
Strana od-do
775-780
Kód UT WoS článku
000336879400010
EID výsledku v databázi Scopus
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