Association of fatty acid profile in plasma lipid fractions with HbA1c in type 2 diabetic patients
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F15%3A39900012" target="_blank" >RIV/00216275:25310/15:39900012 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1007/s13410-015-0399-8" target="_blank" >http://dx.doi.org/10.1007/s13410-015-0399-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s13410-015-0399-8" target="_blank" >10.1007/s13410-015-0399-8</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Association of fatty acid profile in plasma lipid fractions with HbA1c in type 2 diabetic patients
Popis výsledku v původním jazyce
The aim of this pilot study has been the comparison of fatty acid profiles of diabetic and healthy subjects in order to evaluate the relationship between fatty acid profiles in plasma lipid fractions and glycated haemoglobin (HbA1c) in type 2 diabetes (T2D) patients. The fatty acid composition of fasting plasma lipid subfractions has been analyzed in patients (n=26) diagnosed with T2D and in corresponding control group (n=26) of healthy voluntary blood donors. Five subfractions containing phospholipids(PLs), diglycerides (DGs), free fatty acids (FFAs), triglycerides (TGs), and cholesterol esters (CEs) were isolated from plasma samples and separated by thin-layer chromatography. Fatty acid composition of these subfractions was analyzed by GC/FID. Significant changes in fatty acid profiles were found in all lipid fractions from T2D patients in comparison with the control group. HbA1c correlated negatively with delta 9 desaturation (9D) index. Significantly positive correlation of palmit
Název v anglickém jazyce
Association of fatty acid profile in plasma lipid fractions with HbA1c in type 2 diabetic patients
Popis výsledku anglicky
The aim of this pilot study has been the comparison of fatty acid profiles of diabetic and healthy subjects in order to evaluate the relationship between fatty acid profiles in plasma lipid fractions and glycated haemoglobin (HbA1c) in type 2 diabetes (T2D) patients. The fatty acid composition of fasting plasma lipid subfractions has been analyzed in patients (n=26) diagnosed with T2D and in corresponding control group (n=26) of healthy voluntary blood donors. Five subfractions containing phospholipids(PLs), diglycerides (DGs), free fatty acids (FFAs), triglycerides (TGs), and cholesterol esters (CEs) were isolated from plasma samples and separated by thin-layer chromatography. Fatty acid composition of these subfractions was analyzed by GC/FID. Significant changes in fatty acid profiles were found in all lipid fractions from T2D patients in comparison with the control group. HbA1c correlated negatively with delta 9 desaturation (9D) index. Significantly positive correlation of palmit
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CE - Biochemie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
International Journal of Diabetes in Developing Countries
ISSN
0973-3930
e-ISSN
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Svazek periodika
Neuveden
Číslo periodika v rámci svazku
May 2015
Stát vydavatele periodika
IN - Indická republika
Počet stran výsledku
11
Strana od-do
1-11
Kód UT WoS článku
000373106100005
EID výsledku v databázi Scopus
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