Sensitive approach for voltammetric determination of anti-inflammatory drug sulfasalazine using liquid mercury free silver solid amalgam electrode

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F17%3A39910920" target="_blank" >RIV/00216275:25310/17:39910920 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00706-016-1823-6" target="_blank" >http://dx.doi.org/10.1007/s00706-016-1823-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00706-016-1823-6" target="_blank" >10.1007/s00706-016-1823-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Sensitive approach for voltammetric determination of anti-inflammatory drug sulfasalazine using liquid mercury free silver solid amalgam electrode

Popis výsledku v původním jazyce

Voltammetric study of the anti-inflammatory drug sulfasalazine was investigated employing polished silver solid amalgam electrode. One reduction and appropriate oxidation peak were recorded in a wide range of pH. The reduction peak was well developed and easily evaluable, and thus, it was chosen for further examination. The highest reduction response was observed in citrate buffer of pH 5 about the potential Ep = -0.1 V vs. Ag|AgCl. Parameters of adsorptive stripping square wave voltammetry were optimized, and it was reached excellent repeatability of measurements (RSD = 2.79 %) and determinations (RSD 5.33 %) as well, low limit of detection (LOD = 2.5 9 10-9 mol dm-3) and quantification (LOQ = 8.3 9 10-9 mol dm-3). Developed method was applied to the analysis of pharmaceutical preparation with excellent recovery (96.99–102.52 %). The designed method provides ‘‘environmental friendly’’ tool for sulfasalazine analysis and brings simple and sensitive tool for its determination.

Název v anglickém jazyce

Sensitive approach for voltammetric determination of anti-inflammatory drug sulfasalazine using liquid mercury free silver solid amalgam electrode

Popis výsledku anglicky

Voltammetric study of the anti-inflammatory drug sulfasalazine was investigated employing polished silver solid amalgam electrode. One reduction and appropriate oxidation peak were recorded in a wide range of pH. The reduction peak was well developed and easily evaluable, and thus, it was chosen for further examination. The highest reduction response was observed in citrate buffer of pH 5 about the potential Ep = -0.1 V vs. Ag|AgCl. Parameters of adsorptive stripping square wave voltammetry were optimized, and it was reached excellent repeatability of measurements (RSD = 2.79 %) and determinations (RSD 5.33 %) as well, low limit of detection (LOD = 2.5 9 10-9 mol dm-3) and quantification (LOQ = 8.3 9 10-9 mol dm-3). Developed method was applied to the analysis of pharmaceutical preparation with excellent recovery (96.99–102.52 %). The designed method provides ‘‘environmental friendly’’ tool for sulfasalazine analysis and brings simple and sensitive tool for its determination.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Monatshefte fur Chemie

ISSN

0026-9247

e-ISSN

—

Svazek periodika

148

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

10

Strana od-do

399-408

Kód UT WoS článku

000396528600002

EID výsledku v databázi Scopus

—