Synthesis, spectral, magnetic properties, electrochemical evaluation and SOD mimetic activity of four mixed-ligand Cu(II) complexes
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F17%3A39911356" target="_blank" >RIV/00216275:25310/17:39911356 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.ica.2016.10.034" target="_blank" >http://dx.doi.org/10.1016/j.ica.2016.10.034</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ica.2016.10.034" target="_blank" >10.1016/j.ica.2016.10.034</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Synthesis, spectral, magnetic properties, electrochemical evaluation and SOD mimetic activity of four mixed-ligand Cu(II) complexes
Popis výsledku v původním jazyce
Four new methylsalicylato copper(II) complexes with formula [Cu(4-Mesal)(2)(2-Meim)(2)] (1), [Cu(4-Mesal)(2)(im)(2)] (2), [Cu(3-Mesal)(2)(bzim)(2)]center dot 2H(2)O (3), [Cu(5-Mesal)(2)(im)(2)](n) (4) (where 3-Mesal(-) = 3-methylsalicylato, 4(-)Mesal(-) = 4-methylsalicylato, 5-Mesal(-) = 5-methylsalicylato anion, im = imidazole, 2-Meim = 2-methylimidazole and bzim = benzimidazole) are reported. The solid state complexes were characterized by IR, UV-Vis, EPR, X-ray and magnetic measurements. Despite common coordination environment {CuO2N2O'(2)} different supramolecular structures were found for the compounds: 1 is a 1-D supramolecular chain, 2 and 3 form 2-D supramolecular networks and 4 is a 1D coordination polymer. The superoxide dismutase-like (SOD-like) activity of complexes 1-4 was studied in solution by NBT assay, compared with the activity of the parent ligand, copper acetate and native SOD enzyme and correlated to the redox stability determined by cyclic voltammetry. The exceptionally low SOD-like activity of 3, its lower redox reversibility and higher electron-withdrawing ability could be related to the lowest axial distortion of its coordination environment.
Název v anglickém jazyce
Synthesis, spectral, magnetic properties, electrochemical evaluation and SOD mimetic activity of four mixed-ligand Cu(II) complexes
Popis výsledku anglicky
Four new methylsalicylato copper(II) complexes with formula [Cu(4-Mesal)(2)(2-Meim)(2)] (1), [Cu(4-Mesal)(2)(im)(2)] (2), [Cu(3-Mesal)(2)(bzim)(2)]center dot 2H(2)O (3), [Cu(5-Mesal)(2)(im)(2)](n) (4) (where 3-Mesal(-) = 3-methylsalicylato, 4(-)Mesal(-) = 4-methylsalicylato, 5-Mesal(-) = 5-methylsalicylato anion, im = imidazole, 2-Meim = 2-methylimidazole and bzim = benzimidazole) are reported. The solid state complexes were characterized by IR, UV-Vis, EPR, X-ray and magnetic measurements. Despite common coordination environment {CuO2N2O'(2)} different supramolecular structures were found for the compounds: 1 is a 1-D supramolecular chain, 2 and 3 form 2-D supramolecular networks and 4 is a 1D coordination polymer. The superoxide dismutase-like (SOD-like) activity of complexes 1-4 was studied in solution by NBT assay, compared with the activity of the parent ligand, copper acetate and native SOD enzyme and correlated to the redox stability determined by cyclic voltammetry. The exceptionally low SOD-like activity of 3, its lower redox reversibility and higher electron-withdrawing ability could be related to the lowest axial distortion of its coordination environment.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10402 - Inorganic and nuclear chemistry
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2017
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Inorganica Chimica Acta
ISSN
0020-1693
e-ISSN
—
Svazek periodika
455
Číslo periodika v rámci svazku
January
Stát vydavatele periodika
CH - Švýcarská konfederace
Počet stran výsledku
9
Strana od-do
298-306
Kód UT WoS článku
000389167100037
EID výsledku v databázi Scopus
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