Thin TiO2 Coatings by ALD Enhance the Cell Growth on TiO2 Nanotubular and Flat Substrates

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F20%3A39916589" target="_blank" >RIV/00216275:25310/20:39916589 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26620/20:PU138157

Výsledek na webu

<a href="https://pubs.acs.org/doi/10.1021/acsabm.0c00871" target="_blank" >https://pubs.acs.org/doi/10.1021/acsabm.0c00871</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acsabm.0c00871" target="_blank" >10.1021/acsabm.0c00871</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Thin TiO2 Coatings by ALD Enhance the Cell Growth on TiO2 Nanotubular and Flat Substrates

Popis výsledku v původním jazyce

The present work exploits Ti sheets and TiO2 nanotube (TNT) layers and their surface modifications for the proliferation of different cells. Ti sheets with a native oxide layer, Ti sheets with a crystalline thermal oxide layer, and two kinds of TNT layers (prepared via electrochemical anodization) with a defined inner diameter of 12 and 15 nm were used as substrates. A part of the Ti sheets and the TNT layers was additionally coated by thin TiO2 coatings using atomic layer deposition (ALD). An increase in cell growth of WI-38 fibroblasts (&gt;50%), MG-63 osteoblasts (&gt;30%), and SH-SY5Y neuroblasts (&gt;30%) was observed for all materials coated by five cycles ALD compared to their uncoated counterparts. The additional ALD TiO2 coatings changed the surface composition of all materials but preserved their original structure and protected them from unwanted crystallization and shape changes. The presented approach of mild surface modification by ALD has a significant effect on the materials&apos; biocompatibility and is promising toward application in implant materials.

Název v anglickém jazyce

Thin TiO2 Coatings by ALD Enhance the Cell Growth on TiO2 Nanotubular and Flat Substrates

Popis výsledku anglicky

The present work exploits Ti sheets and TiO2 nanotube (TNT) layers and their surface modifications for the proliferation of different cells. Ti sheets with a native oxide layer, Ti sheets with a crystalline thermal oxide layer, and two kinds of TNT layers (prepared via electrochemical anodization) with a defined inner diameter of 12 and 15 nm were used as substrates. A part of the Ti sheets and the TNT layers was additionally coated by thin TiO2 coatings using atomic layer deposition (ALD). An increase in cell growth of WI-38 fibroblasts (&gt;50%), MG-63 osteoblasts (&gt;30%), and SH-SY5Y neuroblasts (&gt;30%) was observed for all materials coated by five cycles ALD compared to their uncoated counterparts. The additional ALD TiO2 coatings changed the surface composition of all materials but preserved their original structure and protected them from unwanted crystallization and shape changes. The presented approach of mild surface modification by ALD has a significant effect on the materials&apos; biocompatibility and is promising toward application in implant materials.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

20506 - Coating and films

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ACS Applied Bio Materials

ISSN

2576-6422

e-ISSN

2576-6422

Svazek periodika

3

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

6447-6456

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85093674833