Addressing polar solvent challenges in the heterogenization of palladium catalysed Hayashi-Miyaura reaction on polymer support

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F23%3A39920802" target="_blank" >RIV/00216275:25310/23:39920802 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S138151482300250X" target="_blank" >https://www.sciencedirect.com/science/article/pii/S138151482300250X</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.reactfunctpolym.2023.105747" target="_blank" >10.1016/j.reactfunctpolym.2023.105747</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Addressing polar solvent challenges in the heterogenization of palladium catalysed Hayashi-Miyaura reaction on polymer support

Popis výsledku v původním jazyce

The development of recyclable heterogeneous catalysts for the palladium-catalysed additions of arylboronic acids to nitrostyrenes is investigated in this study. Two strategies, direct copolymerization and post-modification, are explored for immobilizing chiral isoquinoline-oxazoline ligands onto polymer matrices. Various copolymer formulations are prepared, and their catalytic activity, recyclability, and reaction kinetics are evaluated. The incorporation of polar functional groups into the polymer matrix enhances catalytic properties, albeit with a decrease in reaction rate compared to the homogeneous system. Post-modification using a polystyrenepolyethylene glycol (PS-PEG) support shows promise, resulting in a moderate decrease in reaction rate and satisfactory performance over multiple reaction cycles. The findings provide valuable insights into the immobilization of chiral ligands and highlight the advantages and limitations of different polymer compositions. These results contribute to the development of advanced catalytic systems for the synthesis of biologically relevant compounds.

Název v anglickém jazyce

Addressing polar solvent challenges in the heterogenization of palladium catalysed Hayashi-Miyaura reaction on polymer support

Popis výsledku anglicky

The development of recyclable heterogeneous catalysts for the palladium-catalysed additions of arylboronic acids to nitrostyrenes is investigated in this study. Two strategies, direct copolymerization and post-modification, are explored for immobilizing chiral isoquinoline-oxazoline ligands onto polymer matrices. Various copolymer formulations are prepared, and their catalytic activity, recyclability, and reaction kinetics are evaluated. The incorporation of polar functional groups into the polymer matrix enhances catalytic properties, albeit with a decrease in reaction rate compared to the homogeneous system. Post-modification using a polystyrenepolyethylene glycol (PS-PEG) support shows promise, resulting in a moderate decrease in reaction rate and satisfactory performance over multiple reaction cycles. The findings provide valuable insights into the immobilization of chiral ligands and highlight the advantages and limitations of different polymer compositions. These results contribute to the development of advanced catalytic systems for the synthesis of biologically relevant compounds.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Reactive and Functional Polymers

ISSN

1381-5148

e-ISSN

1873-166X

Svazek periodika

193

Číslo periodika v rámci svazku

December

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

105747

Kód UT WoS článku

001109351200001

EID výsledku v databázi Scopus

2-s2.0-85175419070