Aerosol Transport in a Model of Human Lungs

Kód výsledku v IS VaVaI

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RIV/00216305:26210/11:PU98966

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Aerosol Transport in a Model of Human Lungs

Popis výsledku v původním jazyce

Complex flow structures emerging in human lungs significantly affect deposition of inhaled particles. Therefore flow measurements alongside with deposition measurements have to be performed on the same model geometry. Amount of deposited aerosol particles in different regions of lungs could be measured by several methods. Gamma detection of radioactive tagged particles is subjected to strict regulations and is expensive; gravimetry and fluorometry are thus preferred in current studies. Novel methodologyfor fluorometric measurement of aerosol transport in models of human lungs was developed. Some previously published experiments were performed using condensation of di(2-ethylhexyl) sebacate (DEHS) vapours on fluorescein nuclei. Their authors assumed that fluorescein is necessary for generation of fluorescent particles and they neglected possible fluorescence of DEHS itself. Our analysis of DEHS characteristics indicated that DEHS fluorescence could be detected apart in sufficient rate

Název v anglickém jazyce

Aerosol Transport in a Model of Human Lungs

Popis výsledku anglicky

Complex flow structures emerging in human lungs significantly affect deposition of inhaled particles. Therefore flow measurements alongside with deposition measurements have to be performed on the same model geometry. Amount of deposited aerosol particles in different regions of lungs could be measured by several methods. Gamma detection of radioactive tagged particles is subjected to strict regulations and is expensive; gravimetry and fluorometry are thus preferred in current studies. Novel methodologyfor fluorometric measurement of aerosol transport in models of human lungs was developed. Some previously published experiments were performed using condensation of di(2-ethylhexyl) sebacate (DEHS) vapours on fluorescein nuclei. Their authors assumed that fluorescein is necessary for generation of fluorescent particles and they neglected possible fluorescence of DEHS itself. Our analysis of DEHS characteristics indicated that DEHS fluorescence could be detected apart in sufficient rate

Druh

D - Stať ve sborníku

CEP obor

BK - Mechanika tekutin

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Experimental Fluid Mechanics 2011 Conference Proceedings Volume 1

ISBN

978-80-7372-784-0

ISSN

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e-ISSN

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Počet stran výsledku

9

Strana od-do

281-288

Název nakladatele

Technical University of Liberec

Místo vydání

Liberec, Czech Republic

Místo konání akce

Jičín

Datum konání akce

22. 11. 2011

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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