In vitro structured tree model of the peripheral vascular network

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F21%3APU146435" target="_blank" >RIV/00216305:26210/21:PU146435 - isvavai.cz</a>

Výsledek na webu

<a href="https://dspace5.zcu.cz/bitstream/11025/46012/2/CM2021_Conference_Proceedings-128-131.pdf" target="_blank" >https://dspace5.zcu.cz/bitstream/11025/46012/2/CM2021_Conference_Proceedings-128-131.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

In vitro structured tree model of the peripheral vascular network

Popis výsledku v původním jazyce

The peripheral arterial system consists of small arteries and arterioles, further branching into capillaries. This complex system could be faithfully represented by an asymmetrically structured tree. Such an approach has been used solely in computational analyses, for instance, 1D fluid-structure interaction simulations or multiscale modelling (3D/1D). In vitro flow phantom studies incorporate only pure resistance or two-element Windkessel to mimic the periphery. Thus, the flow and pressure waveforms in these in vitro studies do not qualitatively correspond to those measured in vivo and consequently nor do the input impedance of the periphery, which is rarely shown. To consider the frequency-dependent input impedance of the tree close to that observed in vivo, we created an experimental circuit. It comprises a peristaltic pump as a source of a physiological waveform, an asymmetric structured tree model constructed from commonly available silicon tubes, and a measurement technique for obtaining the inp

Název v anglickém jazyce

In vitro structured tree model of the peripheral vascular network

Popis výsledku anglicky

The peripheral arterial system consists of small arteries and arterioles, further branching into capillaries. This complex system could be faithfully represented by an asymmetrically structured tree. Such an approach has been used solely in computational analyses, for instance, 1D fluid-structure interaction simulations or multiscale modelling (3D/1D). In vitro flow phantom studies incorporate only pure resistance or two-element Windkessel to mimic the periphery. Thus, the flow and pressure waveforms in these in vitro studies do not qualitatively correspond to those measured in vivo and consequently nor do the input impedance of the periphery, which is rarely shown. To consider the frequency-dependent input impedance of the tree close to that observed in vivo, we created an experimental circuit. It comprises a peristaltic pump as a source of a physiological waveform, an asymmetric structured tree model constructed from commonly available silicon tubes, and a measurement technique for obtaining the inp

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10610 - Biophysics

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů