Friction and Lubrication of Eye/Lens/Lid Interface: The Effect of Lubricant and Contact Lens Material

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F23%3APU149203" target="_blank" >RIV/00216305:26210/23:PU149203 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s11249-023-01787-4" target="_blank" >https://link.springer.com/article/10.1007/s11249-023-01787-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11249-023-01787-4" target="_blank" >10.1007/s11249-023-01787-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Friction and Lubrication of Eye/Lens/Lid Interface: The Effect of Lubricant and Contact Lens Material

Popis výsledku v původním jazyce

Irritation of the eye in the case of contact lens users may imply dry eye syndrome (DES), commonly treated by eye drops. The paper focuses on measuring the friction coefficient with the simultaneous observation of lubricating film formation of the simulated eye/lens/lid interface. The experiments are performed in a pin-on-plate setup under the linear reciprocal motion. The contact is lubricated by twelve different solutions as the potential ingredients for eye drops, focusing on the role of mucin, buffer type, and molecular weight (MW) of hyaluronic acid (HA). Two commercially available contact lenses are studied, while overall lens performance is evaluated, among others. The results showed that the lens material, the presence of mucin, and the type of buffer have a decisive influence on the contact behavior. Specifically, it is concluded that the selection of eye drops should reflect the type of lens the wearers use and the conditions of their tear film. The appropriate ingredient for Acuvue Oasys and Biofinity contact lenses is suggested based on the score of the biotribological performance of the lubricant, taking both friction and lubrication into account.

Název v anglickém jazyce

Friction and Lubrication of Eye/Lens/Lid Interface: The Effect of Lubricant and Contact Lens Material

Popis výsledku anglicky

Irritation of the eye in the case of contact lens users may imply dry eye syndrome (DES), commonly treated by eye drops. The paper focuses on measuring the friction coefficient with the simultaneous observation of lubricating film formation of the simulated eye/lens/lid interface. The experiments are performed in a pin-on-plate setup under the linear reciprocal motion. The contact is lubricated by twelve different solutions as the potential ingredients for eye drops, focusing on the role of mucin, buffer type, and molecular weight (MW) of hyaluronic acid (HA). Two commercially available contact lenses are studied, while overall lens performance is evaluated, among others. The results showed that the lens material, the presence of mucin, and the type of buffer have a decisive influence on the contact behavior. Specifically, it is concluded that the selection of eye drops should reflect the type of lens the wearers use and the conditions of their tear film. The appropriate ingredient for Acuvue Oasys and Biofinity contact lenses is suggested based on the score of the biotribological performance of the lubricant, taking both friction and lubrication into account.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20301 - Mechanical engineering

Projekt

<a href="/cs/project/FW01010060" target="_blank" >FW01010060: Výzkum a vývoj farmaceutické suroviny do umělých slz pro léčbu syndromu suchého oka</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Tribology Letters

ISSN

1023-8883

e-ISSN

1573-2711

Svazek periodika

71

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

18

Strana od-do

118-118

Kód UT WoS článku

001072568100002

EID výsledku v databázi Scopus

2-s2.0-85172070994