The orientations of rigid glass fibres in turbulent flows inside a replica of human airways

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F23%3APU150017" target="_blank" >RIV/00216305:26210/23:PU150017 - isvavai.cz</a>

Výsledek na webu

<a href="http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2023.pdf" target="_blank" >http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2023.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The orientations of rigid glass fibres in turbulent flows inside a replica of human airways

Popis výsledku v původním jazyce

The inhalation of fibers has long been recognized for its potential to induce a range of health-related concerns, primarily stemming from their ability to deeply penetrate the lower regions of the human respiratory system (Aust et al. 2011). However, instead of merely perceiving this behavior as a source of health risks, it presents an intriguing opportunity for the targeted delivery of therapeutic agents to the alveoli. This prospect not only captivates with its potential benefits but also holds significant commercial promise. Addressing this challenge, partly due to the limitations of our existing mathematical and computational models, which struggle to accurately predict the delivered dose for individual patients, and advancing our understanding of fiber dynamics in turbulent flows, this contribution introduces new data acquired within a replica of the human trachea and the first airway bifurcation. The measurements were performed under realistic inhalation conditions.

Název v anglickém jazyce

The orientations of rigid glass fibres in turbulent flows inside a replica of human airways

Popis výsledku anglicky

The inhalation of fibers has long been recognized for its potential to induce a range of health-related concerns, primarily stemming from their ability to deeply penetrate the lower regions of the human respiratory system (Aust et al. 2011). However, instead of merely perceiving this behavior as a source of health risks, it presents an intriguing opportunity for the targeted delivery of therapeutic agents to the alveoli. This prospect not only captivates with its potential benefits but also holds significant commercial promise. Addressing this challenge, partly due to the limitations of our existing mathematical and computational models, which struggle to accurately predict the delivered dose for individual patients, and advancing our understanding of fiber dynamics in turbulent flows, this contribution introduces new data acquired within a replica of the human trachea and the first airway bifurcation. The measurements were performed under realistic inhalation conditions.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20303 - Thermodynamics

Projekt

<a href="/cs/project/GA22-20357S" target="_blank" >GA22-20357S: Měření a počítačová simulace transportu vláknitých aerosolů v proudění s vysokými gradienty rychlosti a interakce vláken se stěnou</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů