Impact of inspiration flow resistance of nebulizer on spontaneous breathing pattern and its effect on regional lung deposition

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F23%3APU150047" target="_blank" >RIV/00216305:26210/23:PU150047 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Impact of inspiration flow resistance of nebulizer on spontaneous breathing pattern and its effect on regional lung deposition

Popis výsledku v původním jazyce

Usually, the inspiration flow resistance is discussed in the context of dry powder inhalers. However, can it be important also in the case of nebulizers? The nebulizers are commonly used with spontaneous breathing. There are no studies dealing with the differences in spontaneous breathing caused by the pressure drop of nebulizers. Within this study, we measured the spontaneous breathing of 10 male subjects while they used a nebulizer Pari LC Sprint Star and during the breathing without any nebulizer. The breath recordings were performed by a spirometer SpiroSonic SMART. The flow rate vs. time breathing profiles were recorded. The time scale was normalized in each breathing cycle. The flow rate in each normalized time step was averaged through the recorded cycles and subsequently through the subjects. A significant difference was detected between the breathing profile with and without nebulizer. In the case of the nebulizer usage, the peak inspiration flow rate was significantly lower, and the average

Název v anglickém jazyce

Impact of inspiration flow resistance of nebulizer on spontaneous breathing pattern and its effect on regional lung deposition

Popis výsledku anglicky

Usually, the inspiration flow resistance is discussed in the context of dry powder inhalers. However, can it be important also in the case of nebulizers? The nebulizers are commonly used with spontaneous breathing. There are no studies dealing with the differences in spontaneous breathing caused by the pressure drop of nebulizers. Within this study, we measured the spontaneous breathing of 10 male subjects while they used a nebulizer Pari LC Sprint Star and during the breathing without any nebulizer. The breath recordings were performed by a spirometer SpiroSonic SMART. The flow rate vs. time breathing profiles were recorded. The time scale was normalized in each breathing cycle. The flow rate in each normalized time step was averaged through the recorded cycles and subsequently through the subjects. A significant difference was detected between the breathing profile with and without nebulizer. In the case of the nebulizer usage, the peak inspiration flow rate was significantly lower, and the average

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20302 - Applied mechanics

Projekt

<a href="/cs/project/GA22-20357S" target="_blank" >GA22-20357S: Měření a počítačová simulace transportu vláknitých aerosolů v proudění s vysokými gradienty rychlosti a interakce vláken se stěnou</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů