Ecg Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F05%3APU52787" target="_blank" >RIV/00216305:26220/05:PU52787 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/05:00013328

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Ecg Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Popis výsledku v původním jazyce

The optical mapping of action potentials from heart surface is extensively used as a new possibility of non-invasive recording methods. It employs application of voltage-sensitive dyes (VSDs). Previously, VSDs has been successfully used in myocardial ischemia studies. Our previous Langendorff perfused heart experiments that have suggested shape changes in ECG signals in time and time-frequency domain caused by application of VSD di-4-ANEPPS during optical mapping. These changes went through detailed anaalysis to reveal impact to particular fractions of a heart cycle. The heart cycle was divided into three parts, corresponded to P-Q segments, QRS complexes, and ST-T segments. Dynamic time warping (DTW) is applied to all marked segments in each experimental period (control, loading and washout phase). Variability of ECG parts is measured by means of an optimal path resulting from DTW based on minimum distance between the control signal segments (before the application of VSD) and segment

Název v anglickém jazyce

Ecg Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Popis výsledku anglicky

The optical mapping of action potentials from heart surface is extensively used as a new possibility of non-invasive recording methods. It employs application of voltage-sensitive dyes (VSDs). Previously, VSDs has been successfully used in myocardial ischemia studies. Our previous Langendorff perfused heart experiments that have suggested shape changes in ECG signals in time and time-frequency domain caused by application of VSD di-4-ANEPPS during optical mapping. These changes went through detailed anaalysis to reveal impact to particular fractions of a heart cycle. The heart cycle was divided into three parts, corresponded to P-Q segments, QRS complexes, and ST-T segments. Dynamic time warping (DTW) is applied to all marked segments in each experimental period (control, loading and washout phase). Variability of ECG parts is measured by means of an optimal path resulting from DTW based on minimum distance between the control signal segments (before the application of VSD) and segment

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JD - Využití počítačů, robotika a její aplikace

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Scripta medica

ISSN

1211-3395

e-ISSN

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Svazek periodika

78

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

273-280

Kód UT WoS článku

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EID výsledku v databázi Scopus

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