An Aditional Marker of Ventricular Dyssynchrony

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F15%3APU115364" target="_blank" >RIV/00216305:26220/15:PU115364 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1109/CIC.2015.7408590" target="_blank" >http://dx.doi.org/10.1109/CIC.2015.7408590</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/CIC.2015.7408590" target="_blank" >10.1109/CIC.2015.7408590</a>

Jazyk výsledku

angličtina

Název v původním jazyce

An Aditional Marker of Ventricular Dyssynchrony

Popis výsledku v původním jazyce

Patients suffering from left bundle branch block (LBBB) can be treated by resynchronization therapy (CRT). The QRS duration (QRSd) and QRS morphology are the main selection criteria. Unfortunately, approximately one-third of CRT patients are non-responders. Here we introduce an additional marker capable of distinguishing ventricular dyssynchrony more accurately. Methods: Ultra-high-frequency (UHF, sampling 25kHz) 12-lead ECG, 15-minute resting supine position, was measured. We analyzed 21 LBBB patients selected for CRT, the QRSd min/mean/max was 130/163/190 ms. Amplitude envelopes in the 500-1000 Hz passband were computed and averaged with R-wave trigger for each patient in V1 and V6 leads. V1-V6 dyssynchrony (DYS) was computed as the time difference between UHF amplitude maximums in the V1 and V6 QRS complex region. Results: The DYS parameter min/mean/max was 1/68/115 ms. Patients with a small value of the DYS parameter, in spite of its QRS duration meet CRT criteria (>120 ms), are not expected CRT responders. The DYS parameter indicates ventricular dyssynchrony and can potentially increase the percentage of CRT responders.

Název v anglickém jazyce

An Aditional Marker of Ventricular Dyssynchrony

Popis výsledku anglicky

Patients suffering from left bundle branch block (LBBB) can be treated by resynchronization therapy (CRT). The QRS duration (QRSd) and QRS morphology are the main selection criteria. Unfortunately, approximately one-third of CRT patients are non-responders. Here we introduce an additional marker capable of distinguishing ventricular dyssynchrony more accurately. Methods: Ultra-high-frequency (UHF, sampling 25kHz) 12-lead ECG, 15-minute resting supine position, was measured. We analyzed 21 LBBB patients selected for CRT, the QRSd min/mean/max was 130/163/190 ms. Amplitude envelopes in the 500-1000 Hz passband were computed and averaged with R-wave trigger for each patient in V1 and V6 leads. V1-V6 dyssynchrony (DYS) was computed as the time difference between UHF amplitude maximums in the V1 and V6 QRS complex region. Results: The DYS parameter min/mean/max was 1/68/115 ms. Patients with a small value of the DYS parameter, in spite of its QRS duration meet CRT criteria (>120 ms), are not expected CRT responders. The DYS parameter indicates ventricular dyssynchrony and can potentially increase the percentage of CRT responders.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Computing in Cardiology

ISBN

978-1-5090-0684-7

ISSN

0276-6574

e-ISSN

—

Počet stran výsledku

4

Strana od-do

1-4

Název nakladatele

Neuveden

Místo vydání

Neuveden

Místo konání akce

Nice, France

Datum konání akce

6. 9. 2015

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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