Time-resolved quantitative inter-eye comparison of cardiac cycle-induced blood volume changes in the human retina

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F18%3APU129757" target="_blank" >RIV/00216305:26220/18:PU129757 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.osapublishing.org/boe/abstract.cfm?uri=boe-9-12-6237" target="_blank" >https://www.osapublishing.org/boe/abstract.cfm?uri=boe-9-12-6237</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1364/BOE.9.006237" target="_blank" >10.1364/BOE.9.006237</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Time-resolved quantitative inter-eye comparison of cardiac cycle-induced blood volume changes in the human retina

Popis výsledku v původním jazyce

We describe a low-cost, easy to use binocular instrument to acquire retinal video sequences of both eyes simultaneously. After image registration, cardiac cycle-induced pulsatile light attenuation changes can be measured quantitatively with high spatial and temporal resolution. Parameters such as amplitude, pulse form, and time shift between light attenuation changes can be calculated and compared between eye sides. Deviation from inter-eye symmetry can be not only an early sign of beginning eye diseases such as glaucoma but also a sign of pathological changes in the carotid arteries; hence, this method can improve the early detection of pathological changes. Important features compared to existing monocular instruments are a narrow band light source with the wavelength close to the peak of the blood extinction, and a proportional relationship of image intensity and light intensity, which are the main requirements for quantitative evaluation.

Název v anglickém jazyce

Time-resolved quantitative inter-eye comparison of cardiac cycle-induced blood volume changes in the human retina

Popis výsledku anglicky

We describe a low-cost, easy to use binocular instrument to acquire retinal video sequences of both eyes simultaneously. After image registration, cardiac cycle-induced pulsatile light attenuation changes can be measured quantitatively with high spatial and temporal resolution. Parameters such as amplitude, pulse form, and time shift between light attenuation changes can be calculated and compared between eye sides. Deviation from inter-eye symmetry can be not only an early sign of beginning eye diseases such as glaucoma but also a sign of pathological changes in the carotid arteries; hence, this method can improve the early detection of pathological changes. Important features compared to existing monocular instruments are a narrow band light source with the wavelength close to the peak of the blood extinction, and a proportional relationship of image intensity and light intensity, which are the main requirements for quantitative evaluation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Optics Express

ISSN

2156-7085

e-ISSN

—

Svazek periodika

9

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

18

Strana od-do

6237-6254

Kód UT WoS článku

000451855300027

EID výsledku v databázi Scopus

2-s2.0-85057835544