Tools for Time-Course Simulation in Systems Biology: A Brief Overview

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F21%3APU137949" target="_blank" >RIV/00216305:26220/21:PU137949 - isvavai.cz</a>

Výsledek na webu

<a href="https://academic.oup.com/bib/advance-article/doi/10.1093/bib/bbaa392/6076933?guestAccessKey=ad7949aa-346e-421c-a28d-669d5874a590" target="_blank" >https://academic.oup.com/bib/advance-article/doi/10.1093/bib/bbaa392/6076933?guestAccessKey=ad7949aa-346e-421c-a28d-669d5874a590</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/bib/bbaa392" target="_blank" >10.1093/bib/bbaa392</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Tools for Time-Course Simulation in Systems Biology: A Brief Overview

Popis výsledku v původním jazyce

Dynamic modeling of biological systems is essential for understanding all properties of a given organism as it allows us to look not only at the static picture of an organism but also at its behavior under various conditions. With the increasing amount of experimental data, the number of tools that enable dynamic analysis also grows. However, various tools are based on different approaches, use different types of data, and offer different functions for analyses, so it can be difficult to choose the most suitable tool for a selected type of model. Here, we bring a brief overview containing descriptions of 50 tools for the reconstruction of biological models, their time-course simulation, and dynamic analysis. We examined each tool using test data and divided them based on the qualitative and quantitative nature of the mathematical apparatus they use.

Název v anglickém jazyce

Tools for Time-Course Simulation in Systems Biology: A Brief Overview

Popis výsledku anglicky

Dynamic modeling of biological systems is essential for understanding all properties of a given organism as it allows us to look not only at the static picture of an organism but also at its behavior under various conditions. With the increasing amount of experimental data, the number of tools that enable dynamic analysis also grows. However, various tools are based on different approaches, use different types of data, and offer different functions for analyses, so it can be difficult to choose the most suitable tool for a selected type of model. Here, we bring a brief overview containing descriptions of 50 tools for the reconstruction of biological models, their time-course simulation, and dynamic analysis. We examined each tool using test data and divided them based on the qualitative and quantitative nature of the mathematical apparatus they use.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Briefings in Bioinformatics

ISSN

1467-5463

e-ISSN

1477-4054

Svazek periodika

22

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

15

Strana od-do

1-15

Kód UT WoS článku

000709461800009

EID výsledku v databázi Scopus

2-s2.0-85116172959