A minireview on the bioinformatics analysis of mobile gene elements in microbiome research

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F23%3APU149608" target="_blank" >RIV/00216305:26220/23:PU149608 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027162:_____/23:N0000213

Výsledek na webu

<a href="https://www.frontiersin.org/articles/10.3389/fbrio.2023.1275910/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fbrio.2023.1275910/full</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fbrio.2023.1275910" target="_blank" >10.3389/fbrio.2023.1275910</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A minireview on the bioinformatics analysis of mobile gene elements in microbiome research

Popis výsledku v původním jazyce

The horizontal transfer of mobile gene elements between bacteria plays a crucial role in their evolutionary dynamics. Additionally, it enables the accumulation and dissemination of genes conferring antibiotic and heavy-metal resistance, and thus contributes to the worldwide emergence and spread of drug-resistance pathogens. This process is instrumental in maintaining genetic diversity within bacterial populations and facilitates their adaptation to novel environments. It allows bacteria to acquire genes responsible for the synthesis of enzymes that utilize alternative energy sources and substrates. Furthermore, bacteria can acquire genes associated with toxin production and increased virulence. Horizontal gene transfer serves as a pivotal mechanism in bacterial evolution, enabling the acquisition of novel genetic information and enhancing their capabilities. However, the proper detection and identification of horizontally transferred genes at the microbiome scale is challenging, whether using wet-lab experime

Název v anglickém jazyce

A minireview on the bioinformatics analysis of mobile gene elements in microbiome research

Popis výsledku anglicky

The horizontal transfer of mobile gene elements between bacteria plays a crucial role in their evolutionary dynamics. Additionally, it enables the accumulation and dissemination of genes conferring antibiotic and heavy-metal resistance, and thus contributes to the worldwide emergence and spread of drug-resistance pathogens. This process is instrumental in maintaining genetic diversity within bacterial populations and facilitates their adaptation to novel environments. It allows bacteria to acquire genes responsible for the synthesis of enzymes that utilize alternative energy sources and substrates. Furthermore, bacteria can acquire genes associated with toxin production and increased virulence. Horizontal gene transfer serves as a pivotal mechanism in bacterial evolution, enabling the acquisition of novel genetic information and enhancing their capabilities. However, the proper detection and identification of horizontally transferred genes at the microbiome scale is challenging, whether using wet-lab experime

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/GA22-16786S" target="_blank" >GA22-16786S: Horizontální přenos genů v kuřecím střevním mikrobiomu: detekce a predikce antibiotického rezistomu a mobilomu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in Bacteriology

ISSN

2813-6144

e-ISSN

—

Svazek periodika

2

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

„“-„“

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—