Unfolding Laryngeal Neuromotor Activity in Parkinson's Disease by Phonation Inversion

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F24%3APU152169" target="_blank" >RIV/00216305:26220/24:PU152169 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/chapter/10.1007/978-3-031-61140-7_29" target="_blank" >https://link.springer.com/chapter/10.1007/978-3-031-61140-7_29</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-031-61140-7_29" target="_blank" >10.1007/978-3-031-61140-7_29</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Unfolding Laryngeal Neuromotor Activity in Parkinson's Disease by Phonation Inversion

Popis výsledku v původním jazyce

Neuromotor disorders are a group of neurodegenerative alterations involving the neuromuscular system. Among them, Parkinson's disease (PD) is the one with fastest growing rates. Speech is one of the activities affected by PD, producing strong negative impact on the personal wellbeing of affected people. The present study aimed to characterize PD speech by using a neuromechanical model of phonation by speech inversion methods to estimate the differential activity of the thyroarytenoid and cricothyroid articulations (dNA) under the control of two independent direct neuromotor pathways. The dNA amplitude distributions from persons with PD and age-matched healthy control subjects (HCs) were compared with respect to a mid-age normative database (RSPs). Results show that for the male group 75% of PD and 100% of HC participants were labelled as misaligned to normative. Within the female group misalignments with respect to normative were of 75% in both cases. Regarding the normative participants, 12.5% (males) and 25% (females) were misaligned with respect to their average distributions. This methodology could help in characterizing and explaining neurodegenerative phonation alterations.

Název v anglickém jazyce

Unfolding Laryngeal Neuromotor Activity in Parkinson's Disease by Phonation Inversion

Popis výsledku anglicky

Neuromotor disorders are a group of neurodegenerative alterations involving the neuromuscular system. Among them, Parkinson's disease (PD) is the one with fastest growing rates. Speech is one of the activities affected by PD, producing strong negative impact on the personal wellbeing of affected people. The present study aimed to characterize PD speech by using a neuromechanical model of phonation by speech inversion methods to estimate the differential activity of the thyroarytenoid and cricothyroid articulations (dNA) under the control of two independent direct neuromotor pathways. The dNA amplitude distributions from persons with PD and age-matched healthy control subjects (HCs) were compared with respect to a mid-age normative database (RSPs). Results show that for the male group 75% of PD and 100% of HC participants were labelled as misaligned to normative. Within the female group misalignments with respect to normative were of 75% in both cases. Regarding the normative participants, 12.5% (males) and 25% (females) were misaligned with respect to their average distributions. This methodology could help in characterizing and explaining neurodegenerative phonation alterations.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Lecture Notes in Computer Science: Artificial Intelligence for Neuroscience and Emotional Systems

ISBN

978-3-031-61140-7

ISSN

1611-3349

e-ISSN

—

Počet stran výsledku

10

Strana od-do

300-309

Název nakladatele

SPRINGER INTERNATIONAL PUBLISHING AG

Místo vydání

CHAM

Místo konání akce

Olhao

Datum konání akce

31. 5. 2024

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

001284730300029