Surface Engineering of Piezoelectric Semi-Crystalline Polymer Scaffolds via Plasma Treatment for Improved Adhesion and Integration of Osteoblasts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F26%3A0201510" target="_blank" >RIV/00216305:26220/26:0201510 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.13164/eeict.2025.132" target="_blank" >http://dx.doi.org/10.13164/eeict.2025.132</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.13164/eeict.2025.132" target="_blank" >10.13164/eeict.2025.132</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Surface Engineering of Piezoelectric Semi-Crystalline Polymer Scaffolds via Plasma Treatment for Improved Adhesion and Integration of Osteoblasts

Popis výsledku v původním jazyce

The surface properties of tissue scaffolds are of critical importance in the field of bone tissue engineering as they primarily influence cell adhesion. Piezoelectric semicrystalline synthetic polymers such as polyvinylidene fluoride have attracted considerable attention as biomaterials because of their ability to mimic the electrical environment of the native bone extracellular matrix. However, their osteointegration potential remains limited by their inherently low surface energy and suboptimal cell attachment properties. This study investigated the effect of plasma treatment on the surface properties of PVDF nanofiber scaffolds and the subsequent effects on cell adhesion. The plasma treatment process affects the surface morphology and wettability in relation to the gas used during the modification, thereby enhancing its interaction with the biological environment. Preliminary characterization of these surface modifications was conducted using scanning electron microscopy and water contact angle measurements, while the influence on cell adhesion and infiltration was investigated using confocal laser scanning microscopy.

Název v anglickém jazyce

Surface Engineering of Piezoelectric Semi-Crystalline Polymer Scaffolds via Plasma Treatment for Improved Adhesion and Integration of Osteoblasts

Popis výsledku anglicky

The surface properties of tissue scaffolds are of critical importance in the field of bone tissue engineering as they primarily influence cell adhesion. Piezoelectric semicrystalline synthetic polymers such as polyvinylidene fluoride have attracted considerable attention as biomaterials because of their ability to mimic the electrical environment of the native bone extracellular matrix. However, their osteointegration potential remains limited by their inherently low surface energy and suboptimal cell attachment properties. This study investigated the effect of plasma treatment on the surface properties of PVDF nanofiber scaffolds and the subsequent effects on cell adhesion. The plasma treatment process affects the surface morphology and wettability in relation to the gas used during the modification, thereby enhancing its interaction with the biological environment. Preliminary characterization of these surface modifications was conducted using scanning electron microscopy and water contact angle measurements, while the influence on cell adhesion and infiltration was investigated using confocal laser scanning microscopy.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

20200 - Electrical engineering, Electronic engineering, Information engineering

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings II of the Conference Student Eeict

ISBN

9788021463202

ISSN

—

e-ISSN

2788-1334

Počet stran výsledku

4

Strana od-do

132-135

Název nakladatele

Brno University of Technology

Místo vydání

—

Místo konání akce

Brno

Datum konání akce

29. 4. 2025

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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