The use of comprehensive two-dimensional gas chromatograhy with mass spectrometric detection for the assessment of drug-residue contamination of wastewater and surface water

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F11%3APU93586" target="_blank" >RIV/00216305:26310/11:PU93586 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The use of comprehensive two-dimensional gas chromatograhy with mass spectrometric detection for the assessment of drug-residue contamination of wastewater and surface water

Popis výsledku v původním jazyce

This study is focused on application of analytical method for analysis of selected drug residues from wastewaters and surface waters. Target compounds were acidic drugs mainly from the group of non-steroidal anti-inflammatory drugs (salicylic acid, acetylsalicylic acid, clofibric acid, ibuprofen, acetaminophen, kofein, naproxen, mefenamic acid, ketoprofen, diclofenac). Detection limits of presented method were ranged from 0.18 to 5 ng/L depending on specific compound. The method was successfully appliedfor determination of presence and concentration of selected drug residues in Svratka river and in wastewater from WWTP in Brno. Concentrations of drug residues were ranged from units to tens of ng/L for river water and from units to tens of ug/L for wastewaters. Analytical method used in this study includes solid phase extraction (SPE), derivatization by MSTFA (N-methyl-N-(trimethylsilyl)trifluoroacetamide) and final analysis by orthogonal comprehensive two-dimensional gas chromatograph

Název v anglickém jazyce

The use of comprehensive two-dimensional gas chromatograhy with mass spectrometric detection for the assessment of drug-residue contamination of wastewater and surface water

Popis výsledku anglicky

This study is focused on application of analytical method for analysis of selected drug residues from wastewaters and surface waters. Target compounds were acidic drugs mainly from the group of non-steroidal anti-inflammatory drugs (salicylic acid, acetylsalicylic acid, clofibric acid, ibuprofen, acetaminophen, kofein, naproxen, mefenamic acid, ketoprofen, diclofenac). Detection limits of presented method were ranged from 0.18 to 5 ng/L depending on specific compound. The method was successfully appliedfor determination of presence and concentration of selected drug residues in Svratka river and in wastewater from WWTP in Brno. Concentrations of drug residues were ranged from units to tens of ng/L for river water and from units to tens of ug/L for wastewaters. Analytical method used in this study includes solid phase extraction (SPE), derivatization by MSTFA (N-methyl-N-(trimethylsilyl)trifluoroacetamide) and final analysis by orthogonal comprehensive two-dimensional gas chromatograph

Druh

O - Ostatní výsledky

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů